首页> 外文OA文献 >MORAb-202, an Antibody–Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity

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MORAb-202, an Antibody–Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity

机译：Morab-202，利用人源化抗人富氏菌毒素和微管靶向剂Eribulin的抗体 - 药物缀合物具有效力抗肿瘤活性

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Xin Cheng; Jing Li; Keigo Tanaka; Utpal Majumder; Andrew Z. Milinichik; Arielle C. Verdi; Christopher J. Maddage; Katherine A. Rybinski; Shawn Fernando; Danielle Fernando; Megan Kuc; Keiji Furuuchi; Frank Fang; Toshimitsu Uenaka; Luigi Grasso; Earl F. Albone;
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1. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FR alpha Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity [J] . Cheng Xin, Li Jing, Tanaka Keigo, Molecular cancer therapeutics . 2018,第12期

机译：Morab-202，一种利用人源化抗人类FRαFarletuzumab和微管靶向剂Eribulin的抗体 - 药物缀合物，具有有效的抗肿瘤活性
2. IMGN853, a Folate Receptor-alpha (FR alpha)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FR alpha-Expressing Tumors [J] . Ab Olga, Whiteman Kathleen R., Bartle Laura M., Molecular cancer therapeutics . 2015,第7期

机译：IMGN853，叶酸受体-α（FRα） - 可靶向抗体 - 药物缀合物，表现出针对FRα表达肿瘤的有效的靶向抗肿瘤活性
3. IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML [J] . Kovtun Yelena, Noordhuis Paul, Whiteman Kathleen R., Molecular cancer therapeutics . 2018,第6期

机译：IMGN779是一种具有DNA烷基化活性的新型CD33靶向抗体 - 药物缀合物，在AML的模型中表现出有效的抗肿瘤活性
4. KTN0182A, an Anti-KIT, Pyrrolobenzodiazepine (PBD)-Containing Antibody Drug Conjugate (ADC) Demonstrates Potent Antitumor Activity In Vitro and In Vivo Against a Broad Range of Tumor Types [C] . Sergio Trombetta, Christine Lubeski, Gary C. Kemp, PEGS . 2015

机译：KTN0182A，抗试剂盒，吡咯唑二氮杂己酮（PBD）抗体药物缀合物（ADC）在体外和体内抗抗肿瘤类型的抗肿瘤活性
5. A New Hybrid Agent-Based Model to Evaluate Antibody-Drug Conjugates in Solid Tumors [D] . Menezes, Bruna. 2021

机译：基于杂种代理的基于模型，以评估固体瘤中的抗体 - 药物缀合物
6. Lorvotuzumab mertansine a CD56-targeting antibody-drug conjugate with potent antitumor activity against small cell lung cancer in human xenograft models [O] . Kathleen R Whiteman, Holly A Johnson, Michele F Mayo, 2014

机译：Lorvotuzumab mertansine一种靶向CD56的抗体-药物偶联物在人异种移植模型中具有针对小细胞肺癌的有效抗肿瘤活性
7. IMGN853, a Folate Receptor-α (FRα)–Targeting Antibody–Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors [O] . Olga Ab, Kathleen R. Whiteman, Laura M. Bartle, 2015

机译：IMGN853，叶酸受体-α（FRα） - 可诱导抗体 - 药物缀合物，表现出对表达FRα的肿瘤的有效的靶向抗肿瘤活性
8. Radiation-Induced Chemosensitization: Potentiation of Antitumor Activity of Polymer-Drug Conjugates [R] . Li, C. 2004

机译：辐射诱导的化学增敏作用：增强聚合物 - 药物偶联物的抗肿瘤活性

MORAb-202, an Antibody–Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity

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