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Pyrazolo3,4-dpyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 2: Introduction of cyclic substituents in position 4

机译：Pyrazolo 3,4-D嘧啶作为Sigma-1受体配体，用于治疗疼痛。第2部分：引入4位的环状取代基

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José Luis Díaz; Jordi Corbera; Daniel Martínez; Magda Bordas; Cristina Sicre; Rosalia Pascual; Mª José Pretel; Ana Paz Marín; Ana Montero; Albert Dordal; Inés Alvarez; Carmen Almansa;
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1. Pyrazolo?3,4-d]pyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 2: Introduction of cyclic substituents in position 4 [J] . José Luis Díaz, Jordi Corbera, Daniel Martínez, MedChemComm . 2017,第6期

机译：Pyrazolo？3,4-d]嘧啶作为Sigma-1受体配体用于治疗疼痛。第2部分：引入4位的环状取代基
2. Pyrazolo?3,4-d]pyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 1: 4-acylamino derivatives [J] . José Luis Díaz, Jordi Corbera, Rosa Cuberes, MedChemComm . 2017,第6期

机译：Pyrazolo？3,4-d]嘧啶作为Sigma-1受体配体用于治疗疼痛。第1部分：4-酰基氨基衍生物
3. Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice. [J] . Entrena JM, Cobos EJ, Nieto FR, Pain. . 2009,第3期

机译：Sigma-1受体对于辣椒素诱导的机械超敏性至关重要：使用选择性sigma-1配体和sigma-1敲除小鼠进行的研究。
4. Pyrrolo2,3-dpyrimidine and Pyrazolo3,4-dpyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase [C] . G. Caravatti, J. Bruggen, E. Buchdunger, American Chemical Society . 2001

机译：Pyrrolo 2,3-D嘧啶和吡唑3,4-D嘧啶衍生物作为EGF受体酪氨酸激酶的选择性抑制剂
5. Synthesis and evaluation of novel N-alkylamine derivatives as high affinity sigma-1 receptor ligands. [D] . Chu, Uyen B. 2011

机译：合成和评估新型N-烷基胺衍生物作为高亲和力sigma-1受体配体。
6. Pyrazolo[3,4-d]pyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 2: Introduction of cyclic substituents in position 4 [O] . José Luis Díaz, Jordi Corbera, Daniel Martínez, 1924

机译：吡唑并[3,4-d]嘧啶为sigma-1受体配体，用于治疗疼痛。第2部分：在位置4引入环状取代基
7. Novel pyrazolo3,4-dpyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis [O] . Mai Maher, Asmaa E. Kassab, Ashraf F. Zaher, 2019

机译：新型Pyrozolo 3,4-D嘧啶：设计，合成，抗癌活性，双EGFR / ERBB2受体酪氨酸激酶抑制活性，对细胞周期谱和Caspase-3介导的凋亡的影响
8. Syntheses and Structures of New Pyridino-18-Crown-6 Ligands Containing TwoMethyl, Two t-Butyl or Two Allyl Substituents on Chiral Positions Next to the Pyridine Ring [R] . Habata, Y., Bradshaw, J. S., Young, J. J., 1996

机译：在pyridine环旁边的手性位置上含有两个甲基，两个叔丁基或两个烯丙基取代基的新吡啶基-18-冠-6配体的合成和结构

Pyrazolo3,4-dpyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 2: Introduction of cyclic substituents in position 4

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