首页> 外文OA文献 >Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice

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Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice

机译：CD40激活的增强IL-15Rα表达对于在小鼠的Tramp-C2肿瘤中的IL-15中的抗CD40抗体的协同CD8 T细胞介导的抗肿瘤活性至关重要

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Meili Zhang; Wei Ju; Zhengsheng Yao; Ping Yu; Bih-Rong Wei; R. Mark Simpson; Rebecca Waitz; Marcella Fassò; James P. Allison; Thomas A. Waldmann;
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1. Augmented IL-15Rα expression by CD40 activation is critical in synergistic CD8 T cell-mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice [J] . ZhangM., JuW., YaoZ., The Journal of Immunology: Official Journal of the American Association of Immunologists . 2012,第12期

机译：CD40激活增强的IL-15Rα表达在TRAMP-C2肿瘤小鼠中CD8 T细胞介导的抗CD40抗体与IL-15的协同抗肿瘤活性中至关重要
2. Preassociation of IL-15 with IL-15Rα-IgG1-Fc Enhances Its Activity on Proliferation of NK and CD8+/CD44high T Cells and Its Antitumor Action [J] . Sigrid Dubois, Hiral J. Patel, Meili Zhang, The journal of immunology . 2008,第4期

机译：IL-15与IL-15Rα-IgG1-Fc的预缔合可增强其对NK和CD8 + / CD44high T细胞增殖的活性及其抗肿瘤作用
3. Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents [J] . Weiss Jonathan M., Wiltout Robert H. Oncoimmunology. . 2014,第8期

机译：结合免疫调节剂或靶向剂对激活抗CD40抗体疗法的多方面抗肿瘤反应
4. Combination of Novel HER2 Targeting Antibody 1A12 with Trastuzumab Shows Synergistic Antitumor Activity in HER2 Positive Gastric Cancer [C] . Kyu-Tae Kim, Jong-Seo Lee, Ki-Hyun Kim, PEGS . 2015

机译：具有曲妥珠单抗的新型HER2靶向抗体1a12的组合在HER2阳性胃癌中显示了协同抗肿瘤活性
5. Augmented interleukin (IL) -15Rα expression by CD40 activation is critical in synergistic CD8 T-cell mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice [O] . Meili Zhang, Wei Ju, Zhengsheng Yao, -1

机译：CD40激活的增强白细胞介素（IL）-15rα表达至关重要在单击小鼠的Tramp-C2肿瘤中的抗CD40抗体的协同CD8 T细胞介导的抗肿瘤活性中
6. Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents [O] . Jonathan M Weiss, Robert H Wiltout 2014

机译：对激活抗CD40抗体治疗的多方刻录抗肿瘤反应与免疫调节或靶向剂相结合

Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice

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