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In Vivo Modulation of Vaccine-Induced Immune Responses toward a Th1 Phenotype Increases Potency and Vaccine Effectiveness in a Herpes Simplex Virus Type 2 Mouse Model

机译：体内调制疫苗诱导的免疫应答朝向Th1表型增加疱疹病毒类型2小鼠模型中的效力和疫苗效果

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Jeong-Im Sin; Jong J. Kim; Jean D. Boyer; Richard B. Ciccarelli; Terry J. Higgins; David B. Weiner;
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年度 1999
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1. IL-12 gene as a DNA vaccine adjuvant in a herpes mouse model: IL-12 enhances Th1-type CD4+ T cell-mediated protective immunity against herpes simplex virus-2 challenge. [J] . Sin JI, Kim JJ, Arnold RL, The Journal of Immunology: Official Journal of the American Association of Immunologists . 1999,第5期

机译：IL-12基因作为疱疹小鼠模型中的DNA疫苗佐剂：IL-12增强了Th1型CD4 + T细胞介导的抵抗单纯疱疹病毒2攻击的保护性免疫力。
2. A Paradigm Shift: Vaccine-Induced Antibodies as an Immune Correlate of Protection Against Herpes Simplex Virus Type 1 Genital Herpes [J] . Sita Awasthi Harvey M. Friedman The Journal of Infectious Diseases . 2014,第6期

机译：范式转变：疫苗诱导的抗体作为针对单纯疱疹病毒1型生殖器疱疹的免疫保护相关因子
3. Protective immunity to genital herpes simplex virus type 1 and type 2 provided by self-adjuvanting lipopeptides that drive dendritic cell maturation and elicit a polarized Th1 immune response. [J] . Bettahi I, Zhang X, Afifi RE, Viral immunology . 2006,第2期

机译：通过驱动树突状细胞成熟并引发极化的Th1免疫应答的自我辅助脂肽提供对1型和2型生殖器单纯疱疹病毒的保护性免疫。
4. In-vivo immunofluorescence confocal microscopy of herpes simplex virus type 1 keratitis [C] . Stephen C. Kaufman, M.D., Louisiana State Univ. Eye Ctr., Ophthalmic Technologies VI . 1996

机译：单纯疱疹病毒1型角膜炎的体内免疫荧光共聚焦显微镜检查
5. Immunosuppressive effects of psychological stress and associated increases in glucocorticoids on the T cell-mediated immune response to herpes simplex virus type I. [D] . Ashcraft, Kathleen A. 2010

机译：心理应激的免疫抑制作用以及糖皮质激素的相关增加对T细胞介导的对I型单纯疱疹病毒的免疫反应的影响。
6. In Vivo Modulation of Vaccine-Induced Immune Responses toward a Th1 Phenotype Increases Potency and Vaccine Effectiveness in a Herpes Simplex Virus Type 2 Mouse Model [O] . Jeong-Im Sin, Jong J. Kim, Jean D. Boyer, 1999

机译：疫苗诱导的针对Th1表型的免疫反应的体内调节增加了单纯疱疹病毒2型小鼠模型的效力和疫苗效力。
7. Recombinant Vesicular Stomatitis Virus Vectors Expressing Herpes Simplex Virus Type 2 gD Elicit Robust CD4+ Th1 Immune Responses and Are Protective in Mouse and Guinea Pig Models of Vaginal Challenge [O] . Natuk, Robert J., Cooper, David, Guo, Min, 2006

机译：表达重组疱疹病毒2型gD的重组水泡性口腔炎病毒载体可引发强大的CD4 + Th1免疫反应，并且对小鼠和豚鼠的阴道攻击模型具有保护作用

In Vivo Modulation of Vaccine-Induced Immune Responses toward a Th1 Phenotype Increases Potency and Vaccine Effectiveness in a Herpes Simplex Virus Type 2 Mouse Model

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