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A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit

机译：作用于α亚基C尾的烟碱乙酰胆碱受体的新型α2/α4亚型选择性正变构调制剂

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Jingyi Wang; Alexander Kuryatov; Zhuang Jin; Jack Norleans; Theodore M. Kamenecka; Paul J. Kenny; Jon Lindstrom;
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1. Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant beta Subunits Acquire Sensitivity to alpha 7-Selective Positive Allosteric Modulators [J] . Stokes Clare, Garai Sumanta, Kulkarni Abhijit R., The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2019,第2期

机译：具有突变体β亚基的异孔神经元氰基乙酰胆碱受体对α7选择性阳性变构调节剂的敏感性获得了敏感性
2. The Activity of GAT107, an Allosteric Activator and Positive Modulator of α7 Nicotinic Acetylcholine Receptors (nAChR), Is Regulated by Aromatic Amino Acids That Span the Subunit Interface [J] . Roger L. Papke, Nicole Horenstein, Abhijit R. Kulkarni, The Journal of biological chemistry . 2014,第7期

机译：GAT107的活性，α7烟碱乙酰胆碱受体（NACHR）的变形活化剂和阳性调节剂，由跨越亚基界面的芳族氨基酸调节
3. The subtype-selective nicotinic acetylcholine receptor positive allosteric potentiator 2087101 differentially facilitates neurotransmission in the brain. [J] . de Filippi G, Mogg AJ, Phillips KG, European Journal of Pharmacology: An International Journal . 2010,第2a3期

机译：亚型选择性烟碱型乙酰胆碱受体阳性变构增强剂2087101差异性地促进大脑中的神经传递。
4. Allosteric Modulation of the Nicotinic Acetylcholine Receptor by Physostigmine [C] . LUCIE SVOBODOVá, JAN KRU?EK, TOMá? HENDRYCH, International Biophysics Symposium . 2005

机译：抗碱性乙酰胆碱受体的体溶氨基酮受体
5. Structure-Function Studies of Nicotinic Acetylcholine Receptors Using Selective Agonists and Positive Allosteric Modulators [D] . Marotta, Christopher Bruno 2015

机译：烟碱乙酰胆碱受体的结构功能研究使用选择性激动剂和正变构调节剂。
6. A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit [O] . Jingyi Wang, Alexander Kuryatov, Zhuang Jin, 2015

机译：新型的α2/α4亚型选择性正构构的烟碱型乙酰胆碱受体从α亚基的C尾起作用。
7. Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant β Subunits Acquire Sensitivity to α7-Selective Positive Allosteric Modulators [O] . Clare Stokes, Sumanta Garai, Abhijit R. Kulkarni, 2019

机译：具有突变体β亚基的异孔神经元氰基胆碱受体对α7选择性阳性变构调节剂的敏感性

A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit

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