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Glutathione increase by the n‐butanoyl glutathione derivative (GSH‐C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus

机译：N-丁酰基谷胱甘肽衍生物（GSH-C4）增加谷胱甘肽抑制病毒复制，并在感染的旧小鼠中诱导主要的TH1免疫曲线

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Donatella Amatore; Ignacio Celestino; Serena Brundu; Luca Galluzzi; Paolo Coluccio; Paola Checconi; Mauro Magnani; Anna Teresa Palamara; Alessandra Fraternale; Lucia Nencioni;
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1. Effect of the N-butanoyl glutathione (GSH) derivative and acyclovir on HSV-1 replication and Th1 cytokine expression in human macrophages [J] . FraternaleA., SchiavanoG.F., PaolettiM.F., Medical Microbiology and Immunology . 2014 ,第4期

机译：N-丁酰谷胱甘肽（GSH）衍生物和阿昔洛韦对人巨噬细胞HSV-1复制和Th1细胞因子表达的影响
2. Large-Scale Preparation of N-Butanoyl-L-glutathione (C4-GSH) [J] . Bartoccini Francesca, Mari Michele, Retini Michele, Organic process research & development . 2019 ,第9期

机译：正丁烷酰-L-L-谷胱甘肽（C4-GSH）的大规模制备
3. Carvacrol inhibits the excessive immune response induced by influenza virus A via suppressing viral replication and TLR/RLR pattern recognition [J] . Zheng Ke, Wu Si-zhi, Lv Yi-wen, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2021 ,第1期

机译：Carvacrol抑制流感病毒A通过抑制病毒复制和TLR / RLR模式识别诱导的过度免疫应答
4. VACCINATION WITH VIRAL VECTORS EXPRESSING NP, M1 AND CHIMERIC HEMAGGLUTININ INDUCES BROAD PROTECTION AGAINST INFLUENZA VIRUS CHALLENGE IN MICE [C] . Guha Asthagiri Arunkumar, Meagan McMahon, Vincent Pavot, Conference on vaccine technology VI . 2018

机译：用表达NP，M1和嵌合血凝素的病毒载体接种疫苗可预防小鼠的流感病毒感染
5. Dioxin-induced deregulation of neutrophil recruitment to the lungs of mice infected with influenza virus. [D] . Teske, Sabine. 2006

机译：二恶英诱导的嗜中性粒细胞募集到流感病毒感染小鼠肺部的失调。
6. Antiplatelet Drug Therapy Moderates Immune-Mediated Liver Disease and Inhibits Viral Clearance in Mice Infected with a Replication-Deficient Adenovirus [O] . Matteo Iannacone, Giovanni Sitia, Iñigo Narvaiza, 2007

机译：抗血小板药物疗法可减轻感染复制缺陷型腺病毒的小鼠的免疫介导的肝病并抑制病毒清除。
7. Metabotropic glutamate receptor 3 neuroprotection A. Berent-Spillson and J. W. Russell Received June 12, 2006; revised manuscript received October 3, 2006; accepted October 5, 2006. Address correspondence and reprint requests to James W. Russell, Department of Neurology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201-1595, USA. E-mail: jruss@umich.edu Abbreviations used : APDC , 2 R ,4 R -4-aminopyrrolidine-2,4-dicarboxylate (specific metabotropic glutamate receptor 3 agonist) ; BSO , buthionine sulfoximine (GSH synthesis inhibitor) ; caspase , cysteine-requiring aspartate protease ; CysGly , cysteinylglycine (GSH degradation product) ; DAPI , 4′-6-diamidino-2-phenylindole ; DCF , dichlorodihydrofluorescein ; DCFDA , 5-(and 6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester ; DHE , dihydroethidium ; DRG , dorsal root ganglion ; FCCP , carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (electron transport uncoupler) ; GCP II/III , glutamate carboxypeptidase II/III ; GSH , glutathione ; GSH-EE , glutathione ethyl ester ; GST , glutathione-s-transferase ; H 2 O 2 , hydrogen peroxide ; HBSS , Hank’s balanced salt solution ; JC-1 , 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide ; MCB , monochlorobimane ; mGluR , metabotropic glutamate receptor ; NAAG , N -acetyl-aspartyl-glutamate ; PBS , phosphate-buffered saline ; PCD , programmed cell death ; Rh123 , rhodamine123 ; ROS , reactive oxygen species ; δψ μ , inner mitochondrial membrane potential . Metabotropic glutamate receptor 3 protects neurons from glucose-induced oxidative injury by increasing intracellular glutathione concentration [O] . Berent-Spillson Alison, Russell James W. 2007

机译：代谢型谷氨酸受体3神经保护a. Berent-spillson和J. W. Russell于2006年6月12日收到;修订稿于2006年10月3日收到; 2006年10月5日接受。美国马里兰州巴尔的摩市南格林街22号，马里兰大学医学院神经病学系James W. Russell的地址通信和重印申请。电子邮件：jruss@umich.edu使用的缩写：apDC，2R，4R-4-氨基吡咯烷-2,4-二羧酸酯（特异性代谢型谷氨酸受体3激动剂）; BsO，丁硫氨酸亚砜亚胺（GsH合成抑制剂）;半胱天冬酶，半胱氨酸需要的天冬氨酸蛋白酶; CysGly，半胱氨酰甘氨酸（GsH降解产物）; DapI，4'-6-二脒基-2-苯基吲哚; DCF，二氯二氢荧光素; DCFDa，5-（和6） - 氯甲基-2'，7'-二氯二氢荧光素二乙酸酯，乙酰酯; DHE，二氢乙锭; DRG，背根神经节; FCCp，羰基氰化物4-（三氟甲氧基）苯腙（电子传输解偶联剂）; GCp II / III，谷氨酸羧肽酶II / III;谷胱甘肽;谷胱甘肽; GsH-EE，谷胱甘肽乙酯; GsT，谷胱甘肽-s-转移酶; H 2 O 2，过氧化氢; HBss，Hank的平衡盐溶液; JC-1,5,5'，6,6'-四氯-1,1'，3,3'-四乙基苯并咪唑基酞菁碘化物; mCB，monochlorobimane; mGluR，代谢型谷氨酸受体; NaaG，N-乙酰基 - 天冬氨酰谷氨酸; pBs，磷酸盐缓冲盐水; pCD，程序性细胞死亡; Rh123，罗丹明123;活性氧，活性氧; δψμ，线粒体内膜电位。代谢型谷氨酸受体3通过增加细胞内谷胱甘肽浓度来保护神经元免受葡萄糖诱导的氧化损伤

Glutathione increase by the n‐butanoyl glutathione derivative (GSH‐C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus

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