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Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel

机译：HSP90的抑制下调突变体表皮生长因子受体（EGFR）表达并敏化EGFR突变肿瘤对紫杉醇

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作者
Ayana Sawai; Sarat Chandarlapaty; Heidi Greulich; Mithat Gonen; Qing Ye; Carlos L. Arteaga; William Sellers; Neal Rosen; David B. Solit;
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年度 2008
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1. Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel. [J] . Sawai A, Chandarlapaty S, Greulich H, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2008,第2期

机译：Hsp90的抑制下调突变表皮生长因子受体（EGFR）的表达并使EGFR突变肿瘤对紫杉醇敏感。
2. 543 POSTER Inhibition of Hsp90 function downregulates EGFR and sensitizes EGFR-mutant xenografts to paclitaxel [J] . A.Sawai, H.Greulich, Q.Ye, European Journal of Cancer Supplements . 2006,第12期

机译：543对Hsp90功能的抑制作用下调EGFR，并使EGFR突变异种移植物对紫杉醇敏感
3. Population Pharmacokinetics of ABT-806, an Investigational Anti-Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody, in Advanced Solid Tumor Types Likely to Either Over-Express Wild-Type EGFR or Express Variant III Mutant EGFR [J] . Sharma Shringi, Mittapalli Rajendar K., Holen Kyle D., Clinical pharmacokinetics . 2015,第10期

机译：研究性抗表皮生长因子受体（EGFR）单克隆抗体ABT-806的种群药代动力学，可能是过度表达的野生型EGFR或表达变体III突变型EGFR的晚期实体瘤类型
4. Effect of preoperative cancer treatment on epidermal growth factor receptor (EGFR) receptor expression level in ABY-029 guided sarcoma surgery [C] . Xiaochun Xu, Kimberley S Samkoe, Eric R. Henderson Society of Photo-Optical Instrumentation Engineers;Conference on Molecular-Guided Surgery: Molecules, Devices, and Applications . 2020

机译：术前癌症治疗对ABY-029导向肉瘤手术中表皮生长因子受体（EGFR）受体表达水平的影响
5. Modeling the consequences of epidermal growth factor receptor inhibition in vivo using the classical EGFR⟨wa2⟩ mutant mouse. [D] . Roberts, Reade Bruce. 2003

机译：使用经典的EGFR〈wa2〉突变小鼠对体内表皮生长因子受体抑制的后果进行建模。
6. Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel [O] . Ayana Sawai, Sarat Chandarlapaty, Heidi Greulich, -1

机译：Hsp90的抑制下调突变表皮生长因子受体（EGFR）的表达并使EGFR突变肿瘤对紫杉醇敏感。
7. HER3 ligand heregulin expression and clinical implication in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer treated with EGFR-tyrosine kinase inhibitors [O] . K. Yonesaka, E. Iwama, H. Hayashi, 2019

机译：HER3配体在富尔酪氨酸激酶抑制剂治疗表皮生长因子受体（EGFR） - 矫正非小细胞肺癌患者中表达和临床意义
8. Regulation of Epidermal Growth Factor Receptor (EGFR) Expression by PML in HumanBreast Cancer [R] . Chin, K. V. 1995

机译：pmL对人乳腺癌中表皮生长因子受体（EGFR）表达的调节作用

Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel

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