首页> 外文OA文献 >Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects

【2h】

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects

机译：PF-06751979，一种有效和选择性口服BACE1抑制剂的安全性，可耐受性，药代动力学和药效效应：I阶段I研究健康成人和健康老科对象的结果

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
相似文献
相关主题

著录项

作者
Ruolun Qiu; Jae Eun Ahn; Robert Alexander; Michael A. Brodney; Ping He; Claire Leurent; Jessica Mancuso; Richard A. Margolin; Ekaterina Tankisheva; Danny Chen;
展开▼
作者单位

展开▼
年度 2019
总页数
原文格式 PDF
正文语种
中图分类

相似文献

外文文献
中文文献

1. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects [J] . Qiu Ruolun, Ahn Jae Eun, Alexander Robert, Journal of Alzheimer's disease: JAD . 2019,第2期

机译：PF-06751979，一种有效和选择性口服Bace1抑制剂的安全性，耐受性，药代动力学和药效效应：I阶段的健康成人和健康老科对象的结果
2. First‐in‐Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers [J] . Fox Jonathan C., Hellawell Jennifer L., Rao Satish, Clinical pharmacology in drug development . 2020,第1期

机译：AG10的第一次人类研究，一种用于治疗Transthyretin淀粉样蛋白症状的新型，口服，特异性，选择性和有效的Transthyretin稳定剂：健康成人志愿者的1期安全性，耐受性，药代动力学和药效学研究
3. First-in-Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers [J] . Progress in Artificial Intelligence . 2020,第1期

机译：AG10的首先研究，一种用于治疗Transthyretin淀粉样蛋白症的新型，口服，特异性，选择性和有效的Transthyretin稳定剂：健康成人志愿者的第1期安全性，耐受性，药代动力学和药效学研究
4. Safety, tolerability, pharmacodynamics and pharmacokinetics following single subcutaneous dosesof a teverelix depot formulation in healthy male volunteers [C] . C. MacLean, F. Larsen, R. Piechatzek, Annual meeting exposition of the Controlled Release Society . 2005

机译：在健康男性志愿者中单次皮下注射Teverelix储库制剂后的安全性，耐受性，药效动力学和药代动力学
5. Pharmacokinetic/Pharmacodynamic Analyses of Avatrombopag in Healthy Subjects and Patients with Chronic Liver Disease [D] . NOMOTO, Maiko 2019

机译：阿法曲巴帕在健康受试者和慢性肝病患者中的药代动力学/药效学分析
6. Safety tolerability pharmacokinetics and pharmacodynamics of PF-06650833 a selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor in single and multiple ascending dose randomized phase 1 studies in healthy subjects [O] . Spencer I. Danto, Negin Shojaee, Ravi Shankar P. Singh, 2019

机译：PF-06650833（一种选择性白介素-1受体相关激酶4（IRAK4）抑制剂）在健康受试者的单次和多次递增剂量随机1期研究中的安全性耐受性药代动力学和药效学
7. Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics: results from single oral dose studies in healthy volunteers [O] . Stoch, S Aubrey, Zajic, Stefan, Stone, Julie A, 2013

机译：Odanacatib，一种治疗骨质疏松症的选择性组织蛋白酶K抑制剂：安全性，耐受性，药代动力学和药效学：健康志愿者单次口服剂量研究的结果

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects

著录项

相似文献

相关主题

期刊订阅