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The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice

机译：Dreadd激动剂氯氮平N-氧化物（CNO）对氯氮平反向代谢，并在大鼠和小鼠中产生氯氮平类似的间歇性刺激作用

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Daniel F. Manvich; Kevin A. Webster; Stephanie L. Foster; Martilias S. Farrell; James C. Ritchie; Joseph H. Porter; David Weinshenker;
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年度 2018
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1. The DREADD agonist clozapine N -oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice [J] . Daniel F. Manvich, Kevin A. Webster, Stephanie L. Foster, Scientific reports. . 2018,第1期

机译：Dreadd激动剂氯氮平N-氧化物（CNO）对氯氮平反向代谢，并在大鼠和小鼠中产生氯氮平状的间歇刺激作用
2. Gram scale preparation of clozapine N-oxide (CNO), a synthetic small molecule actuator for muscarinic acetylcholine DREADDs [J] . Phillip L. van der Peet, Christian Gunawan, Alaa Abdul-Ridha, MethodsX . 2018,第1期

机译：克氮平 N -氧化物（CNO）的克规模制备，这是毒蕈碱型乙酰胆碱DREADDs的合成小分子促动器
3. Pharmacokinetic and pharmacodynamic actions of clozapine-N-oxide, clozapine, and compound 21 in DREADD-based chemogenetics in mice [J] . Martin Jendryka, Monika Palchaudhuri, Daniel Ursu, Scientific reports. . 2019,第1期

机译：氯氮平-N-氧化物，氯氮平和化合物21在小鼠基于DREADD的化学发生中的药代动力学和药效学作用
4. Effects of clozapine and alprazolam on cognitive deficits and anxiety-like behaviors in a ketamine-induced rat model of schizophrenia. [D] . Phillips, Jennifer M. 2005

机译：氯氮平和阿普唑仑对氯胺酮诱导的精神分裂症大鼠模型认知缺损和焦虑样行为的影响。
5. The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice [O] . Daniel F. Manvich, Kevin A. Webster, Stephanie L. Foster, -1

机译：DREADD激动剂氯氮平N-氧化物（CNO）被反向代谢为氯氮平并在大鼠和小鼠中产生类氯氮平的感受性刺激作用
6. Clozapine N-Oxide Administration Produces Behavioral Effects in Long–Evans Rats: Implications for Designing DREADD Experiments [O] . Duncan A. A. MacLaren, Richard W. Browne, Jessica K. Shaw, 2016

机译：氯氮平N-氧化物给药在长埃文斯大鼠中产生行为效应：用于设计Dreadd实验的含义
7. Effects of Clozapine and Alprazolam on Cognitive Deficits and Anxiety- Like Behaviors in a Ketamine-Induced Rat Model of Schizophrenia [R] . Phillips, J. M. 2005

机译：氯氮平和阿普唑仑对氯胺酮致精神分裂症大鼠认知功能障碍和焦虑行为的影响

The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice

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