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Clearance of Hepatic Sphingomyelin by Olipudase Alfa Is Associated With Improvement in Lipid Profiles in Acid Sphingomyelinase Deficiency

机译：橄榄酶Alfa的肝鞘磷脂素的清除与酸鞘磷脂酶缺乏的脂质谱的改善有关

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Beth L. Thurberg; Melissa P. Wasserstein; Simon A. Jones; Thomas D. Schiano; Gerald F. Cox; Ana Cristina Puga;
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1. Long-term efficacy of olipudase alfa in adults with acid sphingomyelinase deficiency (ASMD): Further clearance of hepatic sphingomyelin is associated with additional improvements in pro- and anti-atherogenic lipid profiles after 3.5 years of treatment [J] . Thurberg Beth L., Diaz George A., Lachmann Robin H., Molecular genetics and metabolism . 2019,第2期

机译：酸性鞘磷脂酶缺乏（ASMD）中橄榄酶Alfa的长期疗效（ASMD）：肝鞘磷酸鞘素的进一步清除与3.5岁治疗后的抗致动脂质谱的额外改进有关
2. Clearance of Hepatic Sphingomyelin by Olipudase Alfa Is Associated With Improvement in Lipid Profiles in Acid Sphingomyelinase Deficiency [J] . Thurberg Beth L., Wasserstein Melissa P., Jones Simon A., American Journal of Surgical Pathology . 2016,第9期

机译：脂酶阿法清除肝鞘磷脂与酸性鞘磷脂酶缺乏症的脂质谱的改善有关。
3. Hepatic pathology of acid sphingomyelinase deficiency: Clearance of sphingomyelin with recombinant human acid sphingomyelinase administration is associated with improvement in pro-atherogenic lipid profiles [J] . Thurberg Beth, Wasserstein Melissa P., Jones Simon A., Molecular genetics and metabolism . 2015,第2期

机译：酸性鞘磷脂酶缺乏症的肝脏病理：重组人酸性鞘磷脂酶清除鞘磷脂与改善促动脉粥样硬化性脂质谱有关
4. Effects of structured lipids containing eicosapentaenoic or docosahexaenoic acid and caprylic acid on serum and liver lipid profiles in rats [C] . Jun-ichi Nagata, Michio Kasai, Satoshi Negishi, International Conference on Food Factors . 2004

机译：大鼠血清和肝脂肪酸纤维素酸的结构化脂质的作用
5. Improvements for the in Vitro to in Vivo Extrapolation of Hepatic Clearance [D] . Bowman, Christine. 2019

机译：肝清除率体外到体内外推法的改进
6. Clearance of Hepatic Sphingomyelin by Olipudase Alfa Is Associated With Improvement in Lipid Profiles in Acid Sphingomyelinase Deficiency [O] . Beth L. Thurberg, Melissa P. Wasserstein, Simon A. Jones, -1

机译：脂蛋白酶阿尔法清除肝鞘磷脂与酸性鞘磷脂酶缺乏症的脂质谱的改善有关。
7. Novel first-dose adverse drug reactions during a phase I trial of olipudase alfa (recombinant human acid sphingomyelinase) in adults with Niemann–Pick disease type B (acid sphingomyelinase deficiency) [O] . Margaret M. McGovern, Melissa P. Wasserstein, Brian Kirmse, 2015

机译：新型第一剂量不良药物在具有Niemann-pick疾病B（酸鞘氨基氨基酶缺乏）的成人中的橄榄酶Alfa（重组人酸鞘氨基氨基酶）试验期间

Clearance of Hepatic Sphingomyelin by Olipudase Alfa Is Associated With Improvement in Lipid Profiles in Acid Sphingomyelinase Deficiency

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