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Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo1,5-apyridine Scaffold: SAR of the Biphenyl Moiety

机译：基于2-羟基吡唑的脱氢酶抑制剂靶向急性髓性白血病1,5-A吡啶支架：联苯部分的SAR

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Stefano Sainas; Marta Giorgis; Paola Circosta; Valentina Gaidano; Davide Bonanni; Agnese C. Pippione; Renzo Bagnati; Alice Passoni; Yaqi Qiu; Carina Florina Cojocaru; Barbara Canepa; Alessandro Bona; Barbara Rolando; Mariia Mishina; Cristina Ramondetti; Barbara Buccinnà; Marco Piccinini; Mohammad Houshmand; Alessandro Cignetti; Enrico Giraudo; Salam Al-Karadaghi; Donatella Boschi; Giuseppe Saglio; Marco L. Lolli;
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1. Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety [J] . Sainas Stefano, Giorgis Marta, Circosta Paola, Journal of Medicinal Chemistry . 2021,第9期

机译：基于2-羟基吡唑的脱氢酶抑制剂靶向急性髓性白血病[1,5-A]吡啶支架：联苯部分的SAR
2. Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors (vol 61, pg 6034, 2018) [J] . Sainas Stefano, Pippione Agnese C., Lupino Elisa, Journal of Medicinal Chemistry . 2019,第3期

机译：使用有效的2-羟基吡嗪[1,5-A]吡啶支架基础人二氢脱氢酶抑制剂（Vol 61，PG 6034,2018）靶向髓样分化
3. Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors [J] . Sainas Stefano, Pippione Agnese C., Lupino Elisa, Journal of Medicinal Chemistry . 2018,第14期

机译：使用有效的2-羟基吡唑[1,5-A]吡啶支架基础人二氢脱氢酶抑制剂靶向髓样分化
4. Pharmacophore-based Discovery of New Human Dihydroorotate Dehydrogenase Inhibitor [C] . Peng Lu, Yubin Wang International conference of molecular simulations and applied informatics technologies . 2012

机译：基于药理学的新型人类二氢乳清酸酯脱氢酶抑制剂的发现
5. Targeting human acute myelogenous leukemia by inhibiting aberrant Wnt/beta-catenin signaling. [D] . Kim, Eleanor. 2014

机译：通过抑制异常的Wnt /β-catenin信号传导靶向人类急性粒细胞性白血病。
6. Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum [O] . Margaret A. Phillips, Ramesh Gujjar, Nicholas A. Malmquist, -1

机译：基于三唑并嘧啶的二氢乳清酸脱氢酶抑制剂对疟原虫恶性疟原虫具有有效的选择性活性
7. Correction to Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo1,5-apyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors [O] . Stefano Sainas, Agnese C. Pippione, Elisa Lupino, 2019

机译：用效率的2-羟基吡唑1,5-A吡啶支架的人二氢脱氢酶抑制剂对靶向髓样分化的校正
8. Quantitative Risk Assessment of Exposures to Butadiene in European Union Occupational Settings Based on the University of Alabama at Birmingham Epidemiology Study: Acute Myelogenous Leukemia, Chronic Lymphocytic Leukemia, and Chronic Myelogenous Leukemia [R] . Silken, R. L., Valdez-Flores, C. 2007

机译：基于阿拉巴马大学伯明翰分校的流行病学研究：急性髓性白血病，慢性淋巴细胞白血病和慢性粒细胞白血病，欧盟职业环境中丁二烯暴露的定量风险评估

Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo1,5-apyridine Scaffold: SAR of the Biphenyl Moiety

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