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In Vitro, Pharmacokinetic, Pharmacodynamic, and Safety Comparisons of Single and Combined Administration of Tiotropium and Salmeterol in COPD Patients Using Different Dry Powder Inhalers

机译：使用不同干粉吸入器的COPD患者单次和盐酸盐和萨米米尔和Salmeterol的单一和组合施用的体外，药代动力学，药效学和安全比较

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Stephen T. Horhota; Jan A. van Noord; Cynthia B. Verkleij; Loek J. Bour; Ashish Sharma; Michael Trunk; Piet J. G. Cornelissen;
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2. Pharmacokinetic, pharmacodynamic, efficacy, and safety data from two randomized, double-blind studies in patients with asthma and an in vitro study comparing two dry-powder inhalers delivering a combination of salmeterol 50 microg and fluticasone pro [J] . Daley-Yates PT, Parkins DA, Thomas MJ, Clinical therapeutics . 2009,第2期

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3. The pharmacokinetics, safety, and tolerability of single, high-strength doses of fluticasone propionate and fluticasone propionate/salmeterol delivered via a novel multidose dry powder inhaler in adolescents and adults with persistent asthma [J] . Nugent Courtney, Yiu Gloria, Song Sharon, The journal of asthma . 2018,第8期

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4. Safety, tolerability, pharmacodynamics and pharmacokinetics following single subcutaneous dosesof a teverelix depot formulation in healthy male volunteers [C] . C. MacLean, F. Larsen, R. Piechatzek, Annual meeting exposition of the Controlled Release Society . 2005

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机译：实体瘤患者口服后评估新型抗肿瘤药2-甲氧基雌二醇（2ME2）的药代动力学与药效关系，代谢和血浆蛋白结合。
6. In Vitro Pharmacokinetic Pharmacodynamic and Safety Comparisons of Single and Combined Administration of Tiotropium and Salmeterol in COPD Patients Using Different Dry Powder Inhalers [O] . Stephen T. Horhota, Jan A. van Noord, Cynthia B. Verkleij, 2015

机译：使用不同干粉吸入器在COPD患者中单次或联合使用噻托铵和沙美特罗的体外药代动力学药效学和安全性比较
7. A multicenter, randomized, double-blind dose-ranging study of glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler compared to the monocomponents and open-label tiotropium dry powder inhaler in patients with moderate-to-severe COPD [O] . Tashkin Donald P., Martinez Fernando J., Rodriguez-Roisin Roberto, 2016

机译：与中成重度COPD患者的单组分和开放标签噻托铵干粉吸入器相比，格隆溴铵/富马酸福莫特罗固定剂量联合剂量吸入器的多中心，随机，双盲剂量范围研究

In Vitro, Pharmacokinetic, Pharmacodynamic, and Safety Comparisons of Single and Combined Administration of Tiotropium and Salmeterol in COPD Patients Using Different Dry Powder Inhalers

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