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Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016

机译：截短的ErbB2受体（的p95ErbB2）由调蛋白通过异二聚体的形成与ErbB3的调节但仍然到双EGFR敏感/ ErbB2的激酶抑制剂GW572016

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Wenle Xia; Lei-Hua Liu; Peter Ho; Neil L Spector;
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1. Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR|[sol]|ErbB2 kinase inhibitor GW572016 [J] . Wenle Xia, Lei-Hua Liu, Peter Ho, Oncogene . 2004,第3期

机译：截短的ErbB2受体（p95ErbB2）受调蛋白通过与ErbB3异源二聚体形成的调控，但仍对双重EGFR | [sol] | ErbB2激酶抑制剂GW572016敏感
2. SYNAPSE-ASSOCIATED EXPRESSION OF AN ACETYLCHOLINE RECEPTOR-INDUCING PROTEIN, ARIA/HEREGULIN, AND ITS PUTATIVE RECEPTORS, ERBB2 AND ERBB3, IN DEVELOPING MAMMALIAN MUSCLE [J] . Moscoso LM., Gautam M., Noakes PG., Developmental biology . 1995,第1期

机译：突触相关的乙酰胆碱受体诱导蛋白，ARIA / HEREGULIN及其受体ERBB2和ERBB3在哺乳动物细胞中的表达
3. Synapse-Associated Expression of an Acetylcholine Receptor-Inducing Protein, ARIA/Heregulin, and Its Putative Receptors, ErbB2 and ErbB3, in Developing Mammalian Muscle [J] . Lisa M. Moscoso, Gerald C. Chu, Medha Gautam, Developmental biology . 1995,第1期

机译：突触相关的乙酰胆碱受体诱导蛋白ARIA / Heregulin及其推定受体ErbB2和ErbB3在发育中的哺乳动物肌肉中的表达。
4. In Vitro Metabolism of an ERBB2 Receptor Tyrosine Kinase Inhibitor: Identification of Metabolites by LC/MS/MS, LC-NMR and Wet Chemistry Techniques [C] . Chandra Prakash, Zhuang Miao, Jie Chen, ASMS Conference on Mass Spectrometry and Allied Topics . 2007

机译：ERBB2受体酪氨酸激酶抑制剂的体外代谢：通过LC / MS / MS，LC-NMR和湿化学技术鉴定代谢物
5. Targeting EGFR and ErbB2 by small molecule tyrosine kinase inhibitors in human colon cancer. [D] . Zhou, Yunfei. 2005

机译：小分子酪氨酸激酶抑制剂在人结肠癌中靶向EGFR和ErbB2。
6. Assessment of epidermal growth factor receptor (EGFR ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb® GW572016) in an expanded panel of human normal and tumour cell lines [O] . D. W. Rusnak, K. J. Alligood, R. J. Mullin, 2007

机译：在人类正常和肿瘤细胞系的扩展面板中评估表皮生长因子受体（EGFRErbB1）和HER2（ErbB2）蛋白的表达水平以及对拉帕替尼（Tykerb®GW572016）的反应
7. Blockade of EGFR and ErbB2 by the Novel Dual EGFR and ErbB2 Tyrosine Kinase Inhibitor GW572016 Sensitizes Human Colon Carcinoma GEO Cells to Apoptosis [O] . Yunfei Zhou, Song Li, Yi P. Hu, 2006

机译：通过新型双EGFR和ERBB2酪氨酸激酶抑制剂GW572016阻断EGFR和ERBB2敏感人结肠癌地理细胞对细胞凋亡

Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016

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