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PIK3CA mutation confers resistance to chemotherapy in triple-negative breast cancer by inhibiting apoptosis and activating the PI3K/AKT/mTOR signaling pathway

机译：Pik3CA突变通过抑制细胞凋亡并激活PI3K / AKT / MTOR信号传导途径来赋予三重阴性乳腺癌化疗的抵抗力

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Huayu Hu; Junyong Zhu; Yuting Zhong; Rui Geng; Yashuang Ji; Qingyu Guan; Chenyan Hong; Yufan Wei; Ningning Min; Aiying Qi; Yanjun Zhang; Xiru Li;
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1. Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR signaling pathway [J] . Jia-Teng Zhong, Jian Yu, Hai-Jun Wang, Tumour biology : . 2017,第5期

机译：内质网应激通过调节PI3K / AKT / mTOR信号通路对人乳腺癌细胞自噬，凋亡和化疗耐药的影响
2. Activation of WNT/beta-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations [J] . Park Ye-Lim, Kim Hwang-Phill, Cho Young-Won, International Journal of Cancer =: Journal International du Cancer . 2019,第2期

机译：激活WNT /β-连环蛋白信号传导导致含PIK3CA突变的结肠直肠癌细胞中双PI3K / MTOR抑制剂的抗性
3. Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells [J] . Hong-Wei Zhang, Jin-Jiao Hu, Ruo-Qiu Fu, Scientific reports. . 2018,第1期

机译：类黄酮通过下调PI3Kγ介导的PI3K / AKT / mTOR / p70S6K / ULK信号通路抑制人乳腺癌细胞的增殖并诱导细胞凋亡和自噬
4. Label-free phosphoproteomics method to investigate signaling pathways downstream of novel PI3K/mTOR inhibitors in cancer cells [C] . Pedro Casado, Juan Carlos Rodriguez-Prados, Sabina Cosulich, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：无标记的磷蛋白质方法，用于研究新型PI3K / MTOR抑制剂在癌细胞中的信号通路
5. Sensitivity of MCF-7 breast cancer cells to anticancer drugs is decreased by activation of the PI3K/PDK/Akt signal transduction pathway. [D] . Navolanic, Patrick M. 2004

机译：通过激活PI3K / PDK / Akt信号转导途径，MCF-7乳腺癌细胞对抗癌药物的敏感性降低。
6. PIK3CA mutation confers resistance to chemotherapy in triple-negative breast cancer by inhibiting apoptosis and activating the PI3K/AKT/mTOR signaling pathway [O] . Huayu Hu, Junyong Zhu, Yuting Zhong, 2021

机译：Pik3CA突变通过抑制细胞凋亡并激活PI3K / AKT / MTOR信号传导途径来赋予三重阴性乳腺癌化疗的抵抗力
7. Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR signaling pathway [O] . Jia-Teng Zhong, Jian Yu, Hai-Jun Wang, 2017

机译：通过调节PI3K / AKT / MTOR信号通路对人乳腺癌细胞自噬，细胞凋亡和化疗抗性的影响

PIK3CA mutation confers resistance to chemotherapy in triple-negative breast cancer by inhibiting apoptosis and activating the PI3K/AKT/mTOR signaling pathway

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