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An Empirical Antigen Selection Method Identifies Neoantigens That Either Elicit Broad Antitumor T-cell Responses or Drive Tumor Growth

机译：经验抗原选择方法识别出宽抗肿瘤T细胞应答或驱动肿瘤生长的新抗原

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Hubert Lam; Lisa K. McNeil; Hanna Starobinets; Victoria L. DeVault; Roger B. Cohen; Przemyslaw Twardowski; Melissa L. Johnson; Maura L. Gillison; Mark N. Stein; Ulka N. Vaishampayan; Arthur P. DeCillis; James J. Foti; Vijetha Vemulapalli; Emily Tjon; Kyle Ferber; Daniel B. DeOliveira; Wendy Broom; Parul Agnihotri; Elizabeth M. Jaffee; Kwok-Kin Wong; Charles G. Drake; Pamela M. Carroll; Thomas A. Davis; Jessica Baker Flechtner;
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1. A nanoparticle vaccine that targets neoantigen peptides to lymphoid tissues elicits robust antitumor T cell responses [J] . Carlos A. Arbelaez, Juan Estrada, Melissa A. Gessner, NPJ vaccines. . 2020,第1期

机译：靶向淋巴组织的Neoantigen肽的纳米粒子疫苗引发鲁棒抗肿瘤T细胞应答
2. Sindbis viral vectors transiently deliver tumor-associated antigens to lymph nodes and elicit diversified antitumor CD8+ T-cell immunity [J] . GranotT., YamanashiY., MerueloD. Molecular therapy: the journal of the American Society of Gene Therapy . 2014,第1期

机译：Sindbis病毒载体可将肿瘤相关抗原瞬时递送至淋巴结，并引发多样化的抗肿瘤CD8 + T细胞免疫力
3. CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response [J] . Kuhn Nicholas F., Purdon Terence J., van Leeuwen Dayenne G., Cancer Cell . 2019,第3期

机译：CD40配体改性的嵌合抗原受体T细胞通过引发内源性抗肿瘤反应来增强抗肿瘤功能
4. Multi-model selection of integrated mechanistic-empirical models describing T-cell response [C] . Mayalu Michaelle N., Asada H.Harry American Control Conference . 2015

机译：描述T细胞反应的综合机械-经验模型的多模型选择
5. PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma. [D] . 野﨑, 結 2019

机译：PD-L1特异性辅助性T细胞表现出有效的抗肿瘤反应：针对头颈部鳞状细胞癌中PD-L1的癌症免疫疗法的新策略。
6. A nanoparticle vaccine that targets neoantigen peptides to lymphoid tissues elicits robust antitumor T cell responses [O] . Carlos A. Arbelaez, Juan Estrada, Melissa A. Gessner, 2020

机译：靶向淋巴组织的Neoantigen肽的纳米粒子疫苗引发鲁棒抗肿瘤T细胞应答
7. Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity [O] . Xiuli Zhang, Samuel Kim, Jasreet Hundal, 2017

机译：乳腺癌新抗原可以诱导CD8 + T细胞应答和抗肿瘤免疫力
8. Augmentation of Antitumor T-Cell Responses by Increasing APC T-Cell C5a/C3a-C5aR/C3aR Interactions. [R] . Medof, M. E. 2013

机译：通过增加apC T细胞C5a / C3a-C5aR / C3aR相互作用来增强抗肿瘤T细胞应答。

An Empirical Antigen Selection Method Identifies Neoantigens That Either Elicit Broad Antitumor T-cell Responses or Drive Tumor Growth

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