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Optimal curing policy for epidemic spreading over a community network with heterogeneous population

机译:异构人群社区网络蔓延的最佳固化政策

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摘要

The design of an efficient curing policy, able to stem an epidemic process atan affordable cost, has to account for the structure of the population contactnetwork supporting the contagious process. Thus, we tackle the problem ofallocating recovery resources among the population, at the lowest cost possibleto prevent the epidemic from persisting indefinitely in the network.Specifically, we analyze a susceptible-infected-susceptible epidemic processspreading over a weighted graph, by means of a first-order mean-fieldapproximation. First, we describe the influence of the contact network on thedynamics of the epidemics among a heterogeneous population, that is possiblydivided into communities. For the case of a community network, ourinvestigation relies on the graph-theoretical notion of equitable partition; weshow that the epidemic threshold, a key measure of the network robustnessagainst epidemic spreading, can be determined using a lower-dimensionaldynamical system. Exploiting the computation of the epidemic threshold, wedetermine a cost-optimal curing policy by solving a convex minimizationproblem, which possesses a reduced dimension in the case of a communitynetwork. Lastly, we consider a two-level optimal curing problem, for which analgorithm is designed with a polynomial time complexity in the network size.
机译:设计了有效的固化政策,能够遏制流行病学过程atan实惠的成本,必须考虑支持传染过程的人口合约网络的结构。因此,我们解决了人口中的恢复资源问题的问题,以最低的成本possibleto阻止疫情在网络中无限期地持续存在。一致地,我们通过第一个分析了加权图中的敏感感染的易感疫情过程预设-Order意味着 - FieldApparatimation。首先,我们描述了联系网络对异构人群中流行病学的对动力学的影响,这可能已经分为社区。对于社区网络的情况,OuRIno取运取决于公平分区的图形理论概念; Weshow认为,疫情阈值是网络鲁棒性againstst展开的关键措施,可以使用低维度系统来确定。利用流行病阈值的计算,通过求解凸起最小化问题,呈现成本最佳的固化策略,该问题在社区网络的情况下具有减少的维度。最后,我们考虑了一个两级的最佳固化问题,其中安静算法在网络尺寸中具有多项式时间复杂性。

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