The article presents the results of a pedagogical experiment that lasted during 2016-2017 academic year, 52 girls aged 15-16years took part in the study. According to the purpose of the study, it was revealed the influence of means of orienteering within the framework of the author's program of physical education on the psychophysiological state of girls aged 15-16 years. We found that during the pedagogical experiment, the positive dynamics of the majority of the studied indicators was observed. The indicators of the functional state, in particular, of the cardiovascular and respiratory systems, were significantly improved. In the15-year-old girls the heart rate at rest decreased by 12.7 % (p<0.01), in the 16 year-old girls - by 11.1 % (p<0.01); the average indicators of the vital capacity of the lungs increased in the girls aged 15 years by 8.0 % (р<0.01), in the girls aged 16 years - by 22.2 % (р<0.01). The average statistical parameters of the Genchi test also were improved significantly, in the girls aged 15 years by 14.6 % (p<0.01), in the girls aged 16 years by 11.8 % (p<0.01). In addition, positive changes occurred in the indicators that characterize cognitive functions. It was significantly improved the short-term memory capacity: in the girls aged 15 and 16 years by 15.3 % (p<0.01) and by 15.5 % (p<0.01), respectively. The information processing capacity increased in the girls aged 15 years by 22.1 % (p<0.01), in the girls aged 16 years - by 29.8 % (p<0.01). Among the motor qualities, the parameters of the sharpened Romberg test have undergone the most positive changes, as in the case of the girls aged 15 years the average index was improved by 26.7 % (p<0.01), in girls aged 16 years by 18.3 % (p<0.01). Significant changes (p<0,05-p<0,01) also occurred in the parameters of running 100 m race, shuttle running 4x9 m and running 1,500 m race, as well as sit-up from the back-lying position.
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