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Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic Origins

机译：日内瓦鸡尾酒的安全性，一种细胞色素P450和p-糖蛋白表型鸡尾酒，来自三种不同地理起源的健康志愿者

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Victoria Rollason; Médéric Mouterde; Youssef Daali; Martina Čížková; Edita Priehodová; Iva Kulichová; Helena Posová; Jitka Petanová; Anwar Mulugeta; Eyasu Makonnen; Abir Al-Habsi; Robin Davidson; Khalid K. Al-Balushi; Khalid Al-Thihli; Marie Cerná; Said Al-Yahyaee; Viktor Černý; Getnet Yimer; Estella S. Poloni; Jules Desmeules;
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1. Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers. [J] . Yeh RF, Gaver VE, Patterson KB, JAIDS: Journal of acquired immune deficiency syndromes . 2006,第1期

机译：洛匹那韦/利托那韦诱导健康志愿者的细胞色素P450酶CYP2C9，CYP2C19和CYP1A2的肝活性，但抑制CYP3A的肝和肠活性。
2. Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots [J] . M Bosilkovska, CF Samer, J Deglon, Clinical Pharmacology and Therapeutics . 2014,第3期

机译：日内瓦鸡尾酒使用干血斑评估细胞色素P450和P-糖蛋白活性
3. Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots [J] . M Bosilkovska, CF Samer, J Deglon, Clinical Pharmacology and Therapeutics . 2014,第3期

机译：以细胞色素P450和p-糖蛋白活动评估的日内瓦鸡尾酒使用干血斑
4. Cocktail approach for microsomal CYP450 phenotyping using UHPLC-QTOF [C] . Dany Spaggiari, Laurent Geiser, Youssef Daali, International Mass Spectrometry Conference . 2014

机译：使用UHPLC-QTOF的微粒体CYP450表型鸡尾酒方法
5. Dietary effects on drug metabolism and transport: Effect of peppermint oil, St. John's Wort, and fruit juices on cytochrome P450 3A4, P-glycoprotein, and organic anion transporting polypeptides in vitro and in humans [D] . Dresser, George K. 2004

机译：饮食对药物代谢和转运的影响：薄荷油，圣约翰草和果汁对体外和人体中细胞色素P450 3A4，P-糖蛋白和有机阴离子转运多肽的影响
6. Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots [O] . M Bosilkovska, C F Samer, J Déglon, -1

机译：日内瓦鸡尾酒使用干血斑评估细胞色素P450和P-糖蛋白活性
7. Geneva cocktail for cytochrome p450 and P-glycoprotein activity assessment using dried blood spots. [O] . Bosilkovska, M., Samer, C.F., Déglon, J., 2014

机译：日内瓦鸡尾酒，用于使用干血斑评估细胞色素p450和P-糖蛋白活性。

Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic Origins

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