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Pre-clinical dose-ranging efficacy, pharmacokinetics, tissue biodistribution, and toxicity of a targeted contrast agent for MRI of amyloid deposition in Alzheimer’s disease

机译：在阿尔茨海默病中淀粉样蛋白沉积MRI的靶向造影剂的临床前剂量范围疗效，药代动力学，组织生物分布和毒性

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Andrew A. Badachhape; Peter K. Working; Mayank Srivastava; Prajwal Bhandari; Igor V. Stupin; Laxman Devkota; Eric A. Tanifum; Ananth V. Annapragada; Ketan B. Ghaghada;
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1. Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI [J] . Bort Guillaume, Catoen Sarah, Borderies Helene, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2014,第Null期

机译：基于d的造影剂靶向淀粉样蛋白聚集物，用于MRI早期诊断阿尔茨海默氏病
2. Pharmacokinetics and Amyloid Plaque Targeting Ability of a Novel Peptide-Based Magnetic Resonance Contrast Agent in Wild-Type and Alzheimer's Disease Transgenic Mice [J] . Karunya K.Kandimalla, Thomas M.Wengenack, Geoffry L Curran The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2007,第2期

机译：新型基于肽的磁共振造影剂在野生型和阿尔茨海默氏病转基因小鼠中的药代动力学和淀粉样蛋白靶向能力
3. Pharmacokinetics and Amyloid Plaque Targeting Ability of a Novel Peptide-Based Magnetic Resonance Contrast Agent in Wild-Type and Alzheimer's Disease Transgenic Mice [J] . Karunya K.Kandimalla, Thomas M.Wengenack, Geoffry L Curran The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2007,第2期

机译：新型基于肽的磁共振造影剂在野生型和阿尔茨海默氏病转基因小鼠中的药代动力学和淀粉样蛋白靶向能力
4. Synthesis of Gadolinium-complexed beta-Amyloid binding peptides as Contrast Agents for MRI diagnosis of Alzheimer's Disease [C] . Matharu B., Spencer N., Howe F, European Conference on Chemistry for Life Sciences . 2011

机译：钆络合物β-淀粉样蛋白结合肽的合成作为阿尔茨海默病的MRI诊断的造影剂
5. Investigations of the biodistribution and phototherapeutic utility of two palladium(II)-containing macrocyclic drugs in a tumour-bearing mouse model: A study of the pharmacokinetics and tissue distribution of the potential photodynamic drug palladium-bacteriopheophorbide as well as the in vivo treatment efficacy and tissue distribution of the potential photothermal drug palladium(II) octabutoxynaphthalocyanine. [D] . DeGroot, Jennifer Leanne. 2002

机译：两种含钯（II）的大环药物在荷瘤小鼠模型中的生物分布和光疗实用性的研究：潜在的光动力药物钯-细菌脱镁叶绿酸的药代动力学和组织分布以及体内治疗效果和研究光热药物钯（II）八丁氧基萘酞菁的组织分布。
6. Iterative Image Processing for Early Diagnostic of Beta-Amyloid Plaque Deposition in Pre-Clinical Alzheimer’s Disease Studies [O] . Nikolai V Slavine, Padmakar V Kulkarni, Roderick W McColl -1

机译：迭代图像处理可在临床前阿尔茨海默氏病研究中早期诊断β-淀粉样蛋白斑沉积
7. Curcumin Targeted, Polymalic Acid-Based MRI Contrast Agent for the Detection of Aβ Plaques in Alzheimer's Disease [O] . Rameshwar Patil, Pallavi R. Gangalum, Shawn Wagner, 2015

机译：姜黄素靶向，基于多种酸的MRI造影剂，用于检测阿尔茨海默病的Aβ斑块

Pre-clinical dose-ranging efficacy, pharmacokinetics, tissue biodistribution, and toxicity of a targeted contrast agent for MRI of amyloid deposition in Alzheimer’s disease

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