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Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors

机译：将脱苯基磺酸盐作为新型乳糖酰络合物1（MTORC1）抑制剂的新型乳糖-TRNA合成酶（LRS）的乳酰基氨基酯的发现

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1. Discovery of novel leucyladenylate sulfamate surrogates as leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors [J] . Suyoung Yoon, Dongxu Zuo, Jong Hyun Kim, Bioorganic and medicinal chemistry . 2018,第14期

机译：将新型脱苯基磺酸盐蛋白酶替代品作为白胶-TRNA合成酶（LRS） - 雷帕霉素络合物1（MTORC1）抑制剂的哺乳动物靶标
2. Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors [J] . Yoon Suyoung, Kim Jong Hyun, Koh Yura, Bioorganic and medicinal chemistry . 2017,第15期

机译：将简化的脱苯基化磺酸盐作为新型白癜全-TRNA合成酶（LRS）的雷帕霉素络合物1（MTORC1）抑制剂的哺乳动物靶标
3. Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors [J] . Yoon Suyoung, Kim Jong Hyun, Kim Sung-Eun, Journal of Medicinal Chemistry . 2016,第22期

机译：作为新的亮氨酰tRNA合成酶（LRS）靶向的雷帕霉素复合物1（mTORC1）抑制剂的哺乳动物目标亮氨酸腺苷磺酸盐的发现。
4. INSULINE LIKE GROWTH FACTOR-1 AND LEUCINE ACTIVATE PIG MYOGENIC SATELLITE CELLS THROUGH MAMMALIAN TARGET OF RAPAMYCIN PATHWAY [C] . L.T.Medeiros, rnJ.C.Pinto, rnE.M.de Castro, Proceedings of 53rd International Congress of Meat Science and Technology . 2007

机译：胰岛素样生长因子-1和亮氨酸通过雷帕霉素途径的哺乳动物靶标激活猪生代卫星细胞
5. Development of selective inhibitors of the mammalian target of rapamycin. [D] . Choi, Jun Yong. 2009

机译：开发雷帕霉素哺乳动物靶标的选择性抑制剂。
6. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity [O] . Jianling Xie, Godwin A. Ponuwei, Claire E. Moore, -1

机译：cAMP通过促进复合物解离并抑制mTOR激酶活性来抑制雷帕霉素复合物1和-2（mTORC1和2）的哺乳动物靶标
7. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity [O] . Xie, Jianling, Ponuwei, Godwin A., Moore, Claire E., 2011

机译：cAMP通过促进复合物解离并抑制mTOR激酶活性来抑制雷帕霉素复合物1和-2（mTORC1和2）的哺乳动物靶标

Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors

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