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Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40

机译：使用小分子依赖性诱导型MyD88 / CD40调节嵌合抗原受体改性T细胞的膨胀和存活

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Aaron E. Foster; Aruna Mahendravada; Nicholas P. Shinners; Wei-Chun Chang; Jeannette Crisostomo; An Lu; Mariam Khalil; Eva Morschl; Joanne L. Shaw; Sunandan Saha; MyLinh T. Duong; Matthew R. Collinson-Pautz; David L. Torres; Tania Rodriguez; Tsvetelina Pentcheva-Hoang; J. Henri Bayle; Kevin M. Slawin; David M. Spencer;
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1. Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40 [J] . Foster Aaron E., Mahendravada Aruna, Shinners Nicholas P., Molecular therapy: the journal of the American Society of Gene Therapy . 2017,第9期

机译：使用小分子依赖性诱导型MyD88 / CD40调节嵌合抗原受体改性T细胞的膨胀和存活
2. Constitutively active MyD88/CD40 costimulation enhances expansion and efficacy of chimeric antigen receptor T cells targeting hematological malignancies [J] . Matthew R. Collinson-Pautz, Wei-Chun Chang, An Lu, Leukemia . 2019,第9期

机译：组成性活性MyD88 / CD40共刺激可增强针对血液恶性肿瘤的嵌合抗原受体T细胞的扩增和功效
3. Large-scale expansion of V gamma 9V delta 2 T cells with engineered K562 feeder cells in G-Rex vessels and their use as chimeric antigen receptor-modified effector cells [J] . Xiao Lin, Chen Can, Li Zhendong, Cytotherapy . 2018,第3期

机译：Vγ9VDelta 2 T细胞大规模扩张，具有G-REX容器中的工程化K562饲养细胞及其作为嵌合抗原受体改性的效应细胞的用途
4. CD40-ACTIVATED B (CD40-B) CELLS LOADED WITH AUTOLOGOUS TUMOR RNA AS A NOVEL ANTIGEN-PRESENTING CELL VACCINE FOR CANINE LYMPHOMA [C] . Amy LaBlanc, Erika L Krick, Beth Overley, Annual conference of the Veterinary Cancer Society . 2008

机译：CD40-活化的B（CD40-B）用自体肿瘤RNA负载，作为犬淋巴瘤的新型抗原呈递细胞疫苗
5. 4-1BB Costimulation Ameliorates T Cell Exhaustion Induced by Antigen Independent Signaling of Chimeric Antigen Receptors [D] . Long, Adrienne Hart 2015

机译：4-1BB共刺激可改善嵌合抗原受体的抗原独立信号转导所致的T细胞衰竭。
6. Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40 [O] . Aaron E. Foster, Aruna Mahendravada, Nicholas P. Shinners, 2017

机译：使用小分子依赖性诱导型MyD88 / CD40调节嵌合抗原受体修饰的T细胞的扩增和存活。
7. Metformin inhibits proliferation and cytotoxicity and induces apoptosis via AMPK pathway in CD19-chimeric antigen receptor-modified T cells [O] . Qian Mu, Miao Jiang, Yuzhu Zhang, 2018

机译：二甲双胍抑制增殖和细胞毒性，并通过CD19-嵌合抗原受体改性T细胞中的AMPK途径诱导细胞凋亡

Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40

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