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A mutation that blocks integrin α4β7 activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis

机译：阻断整联蛋白α4β7活化的突变可防止适应性免疫介导的结肠炎，而不会增加对先天性结肠炎的易感性

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Hailong Zhang; Yajuan Zheng; Youdong Pan; Changdong Lin; Shihui Wang; Zhanjun Yan; Ling Lu; Gaoxiang Ge; Jinsong Li; Yi Arial Zeng; Jianfeng Chen;
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1. A mutation that blocks integrin α4β7 activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis [J] . Hailong Zhang, Yajuan Zheng, Youdong Pan, BMC Biology . 2020,第1期

机译：阻断整联蛋白α4β7活化的突变可防止适应性免疫介导的结肠炎，而不会增加对先天性结肠炎的易感性
2. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus [J] . Joerg Ermann, Wendy S. Garrett, Juhi Kuchroo, Proceedings of the National Academy of Sciences of the United States of America . 2011,第17期

机译：先天性免疫介导的结肠炎的严重程度受细胞因子缺乏诱导的结肠炎易感性-1（Cdcs1）基因座的控制
3. Acute colitis chronically alters epithelial barrier and adaptive and innate immune responses to subsequent colitis re-activation independently of shifts in microbiota composition [J] . Hughes P., Wardill H., Choo J., Neurogastroenterology and motility . 2018,第S1期

机译：急性结肠炎慢性地改变上皮屏障和适应性和先天的免疫应答，随后的结肠炎再激活，独立于微生物群组合物的变化
4. Lymphocyte integrins and the pathogenesis of experimental colitis [C] . M. B. GRISHAM, K. P. PAVLICK Falk Symposium . 2005

机译：淋巴细胞整联和实验性结肠炎的发病机制
5. Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse. [D] . Hassan, Syed Wajahat. 2010

机译：T细胞蛋白酪氨酸磷酸酶杂合小鼠对葡聚糖硫酸钠诱发结肠炎的敏感性增加。
6. A mutation that blocks integrin α4β7 activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis [O] . Hailong Zhang, Yajuan Zheng, Youdong Pan, 2020

机译：阻断整联蛋白α4β7激活的突变可防止适应性免疫介导的结肠炎而不会增加对先天性结肠炎的敏感性
7. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus [O] . Ermann, Joerg, Garrett, Wendy S., Kuchroo, Juhi, 2011

机译：先天性免疫介导的结肠炎的严重程度受细胞因子缺乏诱导的结肠炎易感性-1（Cdcs1）基因座的控制

A mutation that blocks integrin α4β7 activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis

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