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An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19

机译：酶促TMPRSS2测定，用于评估临床候选者和抑制剂的发现作为Covid-19的潜在治疗

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Jonathan H. Shrimp; Stephen C. Kales; Philip E. Sanderson; Anton Simeonov; Min Shen; Matthew D. Hall;
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1. Screening strategy of TMPRSS2 inhibitors by FRET-based enzymatic activity for TMPRSS2-based cancer and COVID-19 treatment [J] . Yeh Chen, Hsueh-Chun Wang, Mien-Chie Hung, American Journal of Cancer Research . 2021,第3期

机译：基于TMPRSS2的癌症和Covid-19治疗的Fret基酶活性筛选TMPRSS2抑制剂的筛选策略
2. Discovery of novel PDE9 inhibitors capable of inhibiting Aβ aggregation as potential candidates for the treatment of Alzheimer’s disease [J] . Tao Su, Tianhua Zhang, Shishun Xie, Scientific reports. . 2016,第1期

机译：发现能够抑制Aβ聚集的新型PDE9抑制剂作为治疗阿尔茨海默氏病的潜在候选药物
3. Discovery and development of an aurora kinase inhibitor clinical candidate using an image-based assay for measuring proliferation, apoptosis, and DNA content. [J] . Catalano SM, McLaughlin J, Hitoshi Y Assay and drug development technologies . 2009,第2期

机译：使用基于图像的测定法检测和测量极光激酶抑制剂临床候选者的增殖，凋亡和DNA含量。
4. Establishing an Assay to Measure the Enzymatic Activity of Human Glandular Kallikrein 2 in Human Seminal Plasma and Clinical Application [C] . Lu Yingli, Xue Baigong, Zhao Hui, 5th International Conference on Bioinformatics and Biomedical Engineering . 2011

机译：建立测定人类精浆中人腺激肽释放酶2酶活性的方法及其临床应用
5. Mass spectrometric assay developments for enzyme kinetics analysis and inhibitor discovery: From simple to multiplex enzymatic systems. [D] . Pi, Na. 2005

机译：用于酶动力学分析和抑制剂发现的质谱分析开发：从简单到多重酶系统。
6. An Enzymatic TMPRSS2 Assay for Assessment of ClinicalCandidates and Discovery of Inhibitors as Potential Treatment of COVID-19 [O] . JonathanH. Shrimp, Stephen C. Kales, Philip E. Sanderson, 2020

机译：用于评估临床的酶促TMPRSS2测定候选者的候选者和发现作为Covid-19的潜在治疗
7. An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19 [O] . -1

机译：酶促TMPRSS2测定，用于评估临床候选者和抑制剂的发现作为Covid-19的潜在治疗

An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19

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