首页> 外文OA文献 >Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8 + T RM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits

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Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8 + T RM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits

机译：封闭PD-1和LAG-3免疫检查点联合疫苗接种恢复抗病毒组织 - 驻留CD8 + T RM细胞的功能，并在HLA转基因兔中减少眼睑疱疹感染和疾病

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Soumyabrata Roy; Pierre-Gregoire Coulon; Swayam Prakash; Ruchi Srivastava; Roger Geertsema; Nisha Dhanushkodi; Cynthia Lam; Vivianna Nguyen; Elyssa Gorospe; Angela M. Nguyen; Stephanie Salazar; Nuha I. Alomari; Wasay R. Warsi; Lbachir BenMohamed;
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1. Blockade of LAG-3 Immune Checkpoint Combined with Therapeutic Vaccination Restore the Function of Tissue-Resident Anti-Viral CD8(+) T Cells and Protect Against Recurrent Ocular Herpes Simplex Infection and Disease [J] . BenMohamed Lbachir, Roy Soumyabrata, Coulon Pierre-Gregoire A., Investigative ophthalmology & visual science . 2019,第9期

机译：延迟滞后-3免疫检查点联合治疗疫苗接种恢复组织常规抗病毒CD8（+）T细胞的功能，并防止复发性眼疱疱疹性感和疾病
2. Blockade of Lymphocyte activation gene-3 (LAG-3) Pathway Improved the Size and Protective Function of Herpes Simplex Virus-Specific CD8(+) T cells against Ocular Herpes Infection and Disease [J] . Nesburn Anthony B., Srivastava Ruchi, Soumyabrata Roy, Investigative ophthalmology & visual science . 2018,第9期

机译：障碍淋巴细胞活化基因-3（LAG-3）途径改善了疱疹病毒特异性CD8（+）T细胞对眼疱感染和疾病的疱疹病毒特异性CD8（+）T细胞的尺寸和保护功能
3. Blockade of Lymphocyte activation gene-3 (LAG-3) Pathway Improved the Size and Protective Function of Herpes Simplex Virus-Specific CD8(+) T cells against Ocular Herpes Infection and Disease [J] . Nesburn Anthony B., Srivastava Ruchi, Soumyabrata Roy, Investigative ophthalmology & visual science . 2018,第9期

机译：障碍淋巴细胞活化基因-3（LAG-3）途径改善了疱疹病毒特异性CD8（+）T细胞对眼疱感染和疾病的疱疹病毒特异性CD8（+）T细胞的尺寸和保护功能
4. The role of dendritic cells in the cornea in the adaptive immune response following Herpes Simplex Virus-1 ocular infection. [D] . Buela, Kristine-Ann. 2015

机译：单纯疱疹病毒1眼感染后，树突状细胞在角膜中的适应性免疫反应中的作用。
5. Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8+ TRM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits [O] . Soumyabrata Roy, Pierre-Gregoire Coulon, Swayam Prakash, 2019

机译：阻断PD-1和LAG-3免疫检查点并结合疫苗接种可恢复抗病毒组织常驻CD8 + TRM细胞的功能并减少HLA转基因兔的眼单纯疱疹感染和疾病
6. Therapeutic Mucosal Vaccination of Herpes Simplex Virus 2-Infected Guinea Pigs with Ribonucleotide Reductase 2 (RR2) Protein Boosts Antiviral Neutralizing Antibodies and Local Tissue-Resident CD4 + and CD8 + T RM Cells Associated with Protection against Recurrent Genital Herpes [O] . Ruchi Srivastava, Soumyabrata Roy, Pierre-Gregoire Coulon, 2019

机译：疱疹病毒的治疗粘膜疫苗疫苗接种核糖核苷酸还原酶2（RR2）蛋白的豚鼠促进抗病毒中和抗体和局部组织 - 驻留CD4 +和CD8 + T RM细胞，与反复性生殖器疱疹的保护相关

Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8 + T RM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits

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