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Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: Effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions

机译：疱疹病毒胸苷激酶基因治疗实验大鼠BT4C胶质瘤模型：胸苷激酶阳性胶质瘤细胞百分比对治疗效果，存活时间和组织反应的影响

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Anu-Maaria Sandmair; Marita Turunen; Kristiina Tyynelä; Sami Loimas; Pauli Vainio; Ritva Vanninen; Matti Vapalahti; Rolf Bjerkvig; Juhani Jänne; Seppo Ylä-Herttuala;
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1. Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy in BT4C rat glioma model [J] . Kristiina Tyynel?, Anu-Maaria Sandmair, Marita Turunen, Cancer gene therapy . 2002,第11期

机译：腺病毒介导的单纯疱疹病毒胸苷激酶基因治疗BT4C大鼠神经胶质瘤模型
2. Cationic liposomes conjugation to recombinant adenoviral vectors containing herpes simplex virus thymidine kinase gene followed by ganciclovir treatment reduces viral antigenicity and maintains antitumor activity in mouse experimental glioma models [J] . Masaaki Mizuno, Yasushi Ryuke, Jun Yoshida Cancer gene therapy . 2002,第10期

机译：阳离子脂质体与包含单纯疱疹病毒胸苷激酶基因的重组腺病毒载体结合，随后更昔洛韦治疗降低病毒抗原性并在小鼠实验性神经胶质瘤模型中维持抗肿瘤活性
3. Adenovirally Delivered Enzyme Prodrug Therapy with Herpes Simplex Virus-Thymidine Kinase in Composite Tissue Free Flaps Shows Therapeutic Efficacy in Rat Models of Glioma [J] . Seth Rohit, Khan Aadil A., Pencavel Timothy D., Plastic and reconstructive surgery . 2015,第2期

机译：腺病毒传递的酶前药疗法与单纯性疱疹病毒-胸苷激酶复合无组织皮瓣中显示胶质瘤大鼠模型的治疗功效。
4. Integrated homology modelling and x-ray study of herpes simplex virus i thymidine kinase A Case Study [C] . Gerd Folkers, NATO NATO advanced study institute on experimental and computational approaches to structure-based drug design . 1998

机译：单纯疱疹病毒的综合同源造型和X射线研究I胸苷激酶案例研究
5. Gene therapy of cancer: Mechanisms of 'bystander effect' killing in cells expressing the herpes simplex virus-thymidine kinase gene and its potential clinical applications [D] . Marini, Frank C., III 1995

机译：癌症的基因治疗：表达单纯疱疹病毒胸苷激酶基因的细胞中“旁观者效应”的杀伤机理及其潜在临床应用
6. Adenovirally delivered enzyme prodrug therapy with herpes simplex virus-thymidine kinase in composite tissue free flaps shows therapeutic efficacy in rat models of glioma [O] . -1

机译：单纯疱疹病毒-胸苷激酶在复合无组织皮瓣中腺病毒递送的酶前药治疗在神经胶质瘤大鼠模型中显示出治疗功效
7. Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy in BT4C rat glioma model [O] . Tyynelä, Kristiina, Sandmair, Anu Maaria, Turunen, Marita, 2002

机译：腺病毒介导的单纯疱疹病毒胸苷激酶基因治疗BT4C大鼠胶质瘤模型

Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: Effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions

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