Prognosis of peracute period of brain ischemic aterotrombotic stroke course on the ground of TNF-α serum levels detection in the first day of disease

摘要

Aim. The results of investigation of 78 patients in acute period of brain ischemic aterotrombotic stroke are given in the article.Methods and results. It was revealed that development of brain ischemic aterotrombotic stroke is accompanied with elevation of TNF-α (Δ%=419,8; p<0,05) in the first day of disease. Serum concentration of TNF-α during first 24 hours of brain ischemic aterotrombotic stroke onset correlates with summary ball on NIH scale in the onset of stroke (R=0,67; p<0,05), modified Rankin’s scale ball on 21st day (R=0,69; p<0,05) and course of the disease.Conclusion. Mathematic model of peracute period of brain ischemic aterotrombotic stroke course prognosis was designed, which was based on TNF-α serum levels detection on the first day of stroke onset. It is characterized with accuracy of 87.2%.