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Isoquinoline Derivatives as Potent, Selective, and Orally Active CRTH2 Antagonists

机译：异喹啉衍生物作为有效，选择性和口服活性Crth2拮抗剂

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Rie Nishikawa-Shimono; Yoshinori Sekiguchi; Madoka Kawamura; Daisuke Wakasugi; Masahumi Kawanishi; Kazuhito Watanabe; Yumiko Asakura; Akiko Takaoka; Tetsuo Takayama;
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1. Isoquinoline Derivatives as Potent, Selective, and Orally Active CRTH2 Antagonists [J] . Rie Nishikawa-Shimono, Yoshinori Sekiguchi, Madoka Kawamura, Chemical and Pharmaceutical Bulletin . 2014,第6期

机译：异喹啉衍生物作为强效，选择性和口服活性CRTH2拮抗剂
2. Isoquinoline Derivatives as Potent, Selective, and Orally Active CRTH2 Antagonists [J] . Chemical and Pharmaceutical Bulletin . 2014,第6期

机译：异喹啉衍生物作为强效，选择性和口服CRTH2拮抗剂
3. Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists. [J] . Padia JK, Field M, Hinton J, Journal of Medicinal Chemistry . 1998,第7期

机译：新型非肽CCK-B拮抗剂：喹唑啉酮衍生物作为有效，选择性和口服活性CCK-B拮抗剂的设计和开发。
4. Replacement of the Tyr~1 Hydroxyl Group of TIPP Peptides with N-(Alky)carboxamido Groups Results in Potent and Selective δ Opioid Agonists or Antagonists [C] . Irena Berezowska, Grazyna Weltrowska, Carole Lemieux American Peptide Symposium . 2009

机译：用N-（烷基）羧酰胺基团的TyR〜1羟基的Tyr〜1羟基导致有效和选择性的δ阿片类毒剂或拮抗剂
5. Potent derivatives of the bradykinin B2 receptor antagonist Hoe 140 containing analogues of arginine and lysine with increased hydrophobicity. [D] . Kennedy, Kevin Joseph. 1999

机译：缓激肽B2受体拮抗剂Hoe 140的强效衍生物含有精氨酸和赖氨酸的类似物，疏水性增强。
6. The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes [O] . Caroline E Gargett, James S Wiley 1997

机译：异喹啉衍生物KN-62是人类淋巴细胞P2Z受体的有效拮抗剂
7. Novel Selective Orally Active CRTH2 Antagonists for Allergic Inflammation Developed from in Silico Derived Hits [O] . -1

机译：新型选择性口服活性CRTH2拮抗剂用于在硅衍生的命中产生的过敏性炎症

Isoquinoline Derivatives as Potent, Selective, and Orally Active CRTH2 Antagonists

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