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The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination

机译：结核硬化-1（TSC1）基因产品Hamartin抑制细胞生长并通过抑制其泛素来增强TSC2产物结带蛋白的表达

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Giovanna Benvenuto; Shaowei Li; Samantha J Brown; Richard Braverman; William C Vass; Jeremy P Cheadle; Dicky JJ Halley; Julian R Sampson; Ralf Wienecke; Jeffrey E DeClue;
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1. Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin. [J] . Hodges AK, Li S, Maynard J, Human Molecular Genetics . 2001,第25期

机译：TSC1和TSC2中的病理突变破坏了mart素和结蛋白之间的相互作用。
2. The tuberous sclerosis gene products hamartin and tuberin are multifunctional proteins with a wide spectrum of interacting partners. [J] . Rosner M, Hanneder M, Siegel N, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2008,第3期

机译：结节性硬化基因产物hamartin和tuberin是多功能蛋白，具有广泛的相互作用伴侣。
3. Tuberous sclerosis complex gene products, tuberin and hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb [J] . Tee AR., Manning BD., Roux PP., Current Biology: CB . 2003,第15期

机译：结节性硬化症复合基因产物tuberin和hamartin通过充当针对Rheb的GTPase激活蛋白复合物来控制mTOR信号传导
4. The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses Proliferation and Invasion of Human Oral Squamous Carcinoma Cells via p53 Independent and MMP, uPAR Dependent Mechanism [C] . EUN JU LEE, JIN HA WHANG, NAM KYEONG JEON, Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：表皮生长因子受体酪氨酸激酶抑制剂ZD1839（Iressa）通过独立于p53和MMP，uPAR依赖性机制抑制人口腔鳞状细胞癌细胞的增殖和侵袭
5. TWO BACTERIOPHAGE T4 GENE PRODUCTS WHICH REGULATE GENE EXPRESSION AFFECT DNA STRUCTURE: I. THE ALC GENE PRODUCT UNFOLDS THE HOST NUCLEOID. II. THE PSET GENE PRODUCT CAN "SHUTTLE" DNA PHOSPHATES FROM 3' TO 5' TERMINI. [D] . SIROTKIN, KARL M. 1978

机译：调节基因表达影响DNA结构的两种噬菌体T4基因产物：I. ALC基因产物使宿主核素折叠。二。 PSET基因产物可以“封闭” 3'至5'末端的DNA磷酸盐。
6. Expression of the TSC2 product tuberin and its target Rap1 in normal human tissues. [O] . R. Wienecke, J. C. Maize Jr, J. A. Reed, 1997

机译：TSC2产物tuberin及其靶标Rap1在正常人组织中的表达。
7. Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb [O] . Tee Andrew R, Manning Brendan D, Roux Philippe P, 2003

机译：结节性硬化复合物基因产物Tuberin和Hamartin通过充当针对Rheb的GTPase激活蛋白复合物来控制mTOR信号传导

The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination

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