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Human Plasma Concentrations of Tolbutamide and Acetaminophen Extrapolated from in vivo Animal Pharmacokinetics Using in vitro Human Hepatic Clearances and Simple Physiologically Based Pharmacokinetic Modeling for Radio-labeled Microdose Clinical Studies

机译：人体血浆浓度与乙酰丁胺烯烃的甲醛和乙酰氨基酚在体内的甲酰胺中外推，使用在体外的人肝脏间隙和用于无线标记微孔临床研究的简单生理学药代动力学建模

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Hiroshi YAMAZAKI; Eriko KUNIKANE; Sayako NISHIYAMA; Norie MURAYAMA; Makiko SHIMIZU; Yuichi SUGIYAMA; Koji CHIBA; Toshihiko IKEDA;
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机译：从体内大鼠药代动力学，人体体外代谢和基于生理学的药代动力学模型推断的口服给药后，人体中1,4-二恶烷的血药浓度
2. Blood concentrations of acrylonitrile in humans after oral administration extrapolated from in vivo rat pharmacokinetics, in vitro human metabolism, and physiologically based pharmacokinetic modeling. [J] . Takano R, Murayama N, Horiuchi K, Regulatory Toxicology and Pharmacology: RTP . 2010,第2期

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4. A Physiologically-Based Pharmacokinetic Model of Methotrexate Incorporating Hepatic Excretion via Multidrug-Resistance-Associated Protein 2 (Mrp2) in Mice, Rats, Dogs, and Humans [C] . Manupat Lohitnavy, Yasong Lu, Ornrat Lohitnavy, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2017

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5. Physiologically-Based Pharmacokinetic Modelling: Pre-Clinical and Clinical Pharmacokinetic Studies [D] . Rodrigues, Clare Louise. 2008

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6. Human Blood Concentrations of Cotinine a Biomonitoring Marker for Tobacco Smoke Extrapolated from Nicotine Metabolism in Rats and Humans and Physiologically Based Pharmacokinetic Modeling [O] . Hiroshi Yamazaki, Kana Horiuchi, Ryohji Takano, 2010

机译：从大鼠和人类的尼古丁代谢推断出人体血液中可替宁的浓度可替宁是一种用于烟草烟雾的生物监测标志物基于生理学的药代动力学模型
7. Blood Concentrations of 1,4-Dioxane in Humans after Oral Administration Extrapolated from In Vivo Rat Pharmacokinetics, In Vitro Human Metabolism, and Physiologically Based Pharmacokinetic Modeling [O] . Ryohji Takano, Norie Murayama, Kana Horiuchi, 2010

机译：人体中1,4-二恶烷血液浓度从体内大鼠药代动力学，体外人类代谢和生理基础的药代动力学建模外推开
8. Support of Study Entitled, 'Metabolism and Pharmacokinetics of Dihydroartemisinin' and 'In Vitro and In Vivo Metabolism of Sodium Artelinate and DQHS in Rats and Humans' [R] . Idowu, O. R. 1998

机译：支持研究题为“双氢青蒿素的代谢和药代动力学”和“大鼠和人类中的artelinate钠和DQHs的体外和体内代谢”

Human Plasma Concentrations of Tolbutamide and Acetaminophen Extrapolated from in vivo Animal Pharmacokinetics Using in vitro Human Hepatic Clearances and Simple Physiologically Based Pharmacokinetic Modeling for Radio-labeled Microdose Clinical Studies

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