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Inhibitory FcγRIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering

机译：通过PH依赖性抗原结合抗体抑制FcγRIIB介导的来自血浆的可溶性抗原清除及FC工程的增强

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Yuki Iwayanagi; Tomoyuki Igawa; Atsuhiko Maeda; Kenta Haraya; Naoko A. Wada; Norihito Shibahara; Ken Ohmine; Takeru Nambu; Genki Nakamura; Futa Mimoto; Hitoshi Katada; Shunsuke Ito; Tatsuhiko Tachibana; Kou-ichi Jishage; Kunihiro Hattori;
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1. Inhibitory Fc gamma RIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering [J] . Iwayanagi Yuki, Igawa Tomoyuki, Maeda Atsuhiko, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2015,第7期

机译：pH依赖性抗原结合抗体抑制血浆中的FcγRIIb介导的可溶性抗原清除及其通过Fc工程增强
2. Current strategies in antibody engineering: Fc engineering and pH-dependent antigen binding, bispecific antibodies and antibody drug conjugates [J] . Karen J. Vincent, Mauro Zurini Biotechnology Journal: Healthcare,Nutrition,Technology . 2012,第12期

机译：抗体工程的当前策略：Fc工程和pH依赖性抗原结合，双特异性抗体和抗体药物偶联物
3. Modulation of the humoral immune response by targeting CD40 and FcgammaRII/III; delivery of soluble but not particulate antigen to CD40 enhances antibody responses with a Th1 bias. [J] . Szekeres Z, Herbath M, Szittner Z, Molecular Immunology . 2011,第1a2期

机译：通过靶向CD40和FcgammaRII / III调节体液免疫反应;可溶性但非颗粒状抗原向CD40的递送增强了Th1偏倚的抗体反应。
4. THE INHIBITORY Fcy-RECEPTOR MB (CD32B) IS HIGHLY EXPRESSED ON CLONAL PLASMA CELLS FROM PATIENTS WITH SYSTEMIC LIGHT-CHAIN (AL) AMYLOIDOSIS AND PROVIDES A TARGET FOR MONOCLONAL ANTIBODY THERAPY [C] . P. Zhou, A B Olshen, E Bonvini, International Symposium on Amyloidosis . 2008

机译：抑制性FCY-受体MB（CD32B）对来自全身轻链（AL）淀粉样蛋白症患者的克隆血浆细胞高度表达，并为单克隆抗体治疗提供靶标
5. The role of Fcgamma receptors on plasmacytoid dendritic cells in antigen presentation and viral immunity. [D] . Flores, Marcella Maria-Melissa. 2009

机译：Fcgamma受体在浆细胞样树突状细胞上的抗原呈递和病毒免疫作用。
6. Inhibitory FcγRIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering [O] . Yuki Iwayanagi, Tomoyuki Igawa, Atsuhiko Maeda, -1

机译：pH依赖性抗原结合抗体抑制血浆中的FcγRIIb介导的可溶性抗原清除及其通过Fc工程增强
7. Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties [O] . G. Wozniak-Knopp, S. Bartl, A. Bauer, 2010

机译：引入免疫球蛋白恒定结构域的结构环中的抗原结合位点：Fc片段与工程化HER2 / Neu结合位点和抗体特性

Inhibitory FcγRIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering

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