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Genomic Profiling of KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer Patients Reveals Novel Mutations in Genes Potentially Associated with Resistance to Anti-EGFR Agents

机译：KRAS / NRAS / BRAF / PIK3CA野生型转移性结肠直肠癌患者的基因组分析揭示了潜在与抗EGFR试剂相关的基因的新突变

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Anna Maria Rachiglio; Matilde Lambiase; Francesca Fenizia; Cristin Roma; Claudia Cardone; Alessia Iannaccone; Antonella De Luca; Marianeve Carotenuto; Daniela Frezzetti; Erika Martinelli; Evaristo Maiello; Fortunato Ciardiello; Nicola Normanno;
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1. Cross-platform comparison of next-generation sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for detecting KRAS/NRAS/BRAF/PIK3CA mutations in cfDNA from metastatic colorectal cancer patients [J] . Xiaojing Xu, Fei Huang, Minlu Cao, Journal of clinical laboratory analysis. . 2021,第9期

机译：下一代测序和基质辅助激光解吸/电离飞行时间质谱法的跨平台比较，用于检测来自转移结直肠癌患者的CFDNA中的KRAS / NRAS / BRAF / PIK3CA突变
2. PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: A systematic review and meta-analysis [J] . MaoC., YangZ.Y., HuX.F., Annals of oncology: official journal of the European Society for Medical Oncology . 2012,第6期

机译：PIK3CA外显子20突变作为KRAS野生型转移性结直肠癌中抗EGFR单克隆抗体耐药的潜在生物标志物：系统评价和荟萃分析
3. Elucidating the prognostic significance of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese patients with metastatic colorectal cancer [J] . Ma Brigette B., Mo Frankie, Tong Joanna H., Asia-Pacific journal of clinical oncology . 2015,第2期

机译：阐明中国转移性大肠癌患者KRAS，NRAS，BRAF和PIK3CA突变的预后意义
4. Isolation of Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer Using Label-Free Microfluidic Technology for Enumeration and Detection of KRAS, BRAF, PIK3CA Mutation [C] . Haiyan Emily Liu, Evelyn Kidess-Sigal, Melanie Triboulet, International Molecular Medicine Tri-Conference. . 2016

机译：使用无标记微流体技术分离转移性结肠直肠癌患者的循环肿瘤细胞进行募准和检测KRA，BRAF，PIK3CA突变
5. Glucose deprivation selects for KRAS and BRAF mutations in colorectal cancer. [D] . Yun, Jihye. 2009

机译：葡萄糖剥夺选择结直肠癌中的KRAS和BRAF突变。
6. Genomic Profiling of KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer Patients Reveals Novel Mutations in Genes Potentially Associated with Resistance to Anti-EGFR Agents [O] . Anna Maria Rachiglio, Matilde Lambiase, Francesca Fenizia, 2019

机译：KRAS / NRAS / BRAF / PIK3CA野生型转移性结直肠癌患者的基因组分析揭示了可能与抗EGFR药物耐药相关的基因新突变
7. PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis [O] . C. Mao, Z.Y. Yang, X.F. Hu, 2012

机译：Pik3Ca Exon 20突变作为潜在的抗EGFR单克隆抗体在KRAS野生型转移性结肠直肠癌中的潜在生物标志物：系统审查和荟萃分析

Genomic Profiling of KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer Patients Reveals Novel Mutations in Genes Potentially Associated with Resistance to Anti-EGFR Agents

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