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Clinically Relevant Epithelial Lining Fluid Concentrations of Meropenem with Ciprofloxacin Provide Synergistic Killing and Resistance Suppression of Hypermutable Pseudomonas aeruginosa in a Dynamic Biofilm Model

机译：环丙沙星的临床相关上皮衬里液浓度为氟哌氟氟苯甲嘧啶提供了一种动态生物膜模型中高压假单胞菌铜绿假单胞菌的协同杀灭与抗性抑制

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Hajira Bilal; Phillip J. Bergen; Jessica R. Tait; Steven C. Wallis; Anton Y. Peleg; Jason A. Roberts; Antonio Oliver; Roger L. Nation; Cornelia B. Landersdorfer;
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1. Synergistic Meropenem-Tobramycin Combination Dosage Regimens against Clinical Hypermutable Pseudomonas aeruginosa at Simulated Epithelial Lining Fluid Concentrations in a Dynamic Biofilm Model [J] . Bilal Hajira, Bergen Phillip J., Kim Tae Hwan, Antimicrobial agents and chemotherapy. . 2019,第11期

机译：在动态生物膜模型中模拟上皮衬里流体浓度的临床高估假单胞菌铜霉素组合剂量方案
2. Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance [J] . Walsh Clare C., Landersdorfer Cornelia B., McIntosh Michelle P., The Journal of Antimicrobial Chemotherapy . 2016,第8期

机译：临床相关浓度的磷霉素与多粘菌素B，妥布霉素或环丙沙星合用可增强铜绿假单胞菌的细菌杀灭作用，但不能抑制磷霉素耐药性的出现
3. In vitro killing of Escherichia coli, Staphylococcus pseudintermedius and Pseudomonas aeruginosa by enrofloxacin in combination with its active metabolite ciprofloxacin using clinically relevant drug concentrations in the dog and cat. [J] . Blondeau J. M., Borsos S., Blondeau L. D., Veterinary Microbiology . 2012,第2a4期

机译：恩诺沙星及其活性代谢产物环丙沙星联合使用恩罗沙星体外杀死大肠埃希氏菌，假单胞菌葡萄球菌和铜绿假单胞菌狗和猫的临床相关药物浓度。
4. Adaptive optimal therapy design: Integration of pharmacogenetics, pharmacokinetics and pharmacodynamics for the suppression of the emergence of antibiotic resistance (Streptococcus pneumoniae, Pseudomonas aeruginosa). [D] . Jumbe, Nelson L'ntshotshole. 2001

机译：适应性最佳治疗设计：整合药物遗传学，药代动力学和药效学以抑制抗生素耐药性（肺炎链球菌，铜绿假单胞菌）的出现。
5. Clinically Relevant Epithelial Lining Fluid Concentrations of Meropenem with Ciprofloxacin Provide Synergistic Killing and Resistance Suppression of Hypermutable Pseudomonas aeruginosa in a Dynamic Biofilm Model [O] . Hajira Bilal, Phillip J. Bergen, Jessica R. Tait, 2020

机译：环丙沙星的临床相关上皮衬里液浓度为氟哌氟氟苯甲嘧啶提供了一种动态生物膜模型中高压假单胞菌铜绿假单胞菌的协同杀灭与抗性抑制
6. Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing ofPseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance [O] . Clare C. Walsh, Cornelia B. Landersdorfer, Michelle P. McIntosh, 2016

机译：临床相关浓度的FOSFOMYCIN联合多粘菌素B，染发蛋白或环丙沙星增强细菌杀死普通菌铜绿假单胞菌，但不抑制福染霉素抗性的出现
7. Treatment of Pseudomonas aeruginosa Biofilm Infected Wounds with Clinical Wound Care Strategies: A Quantitative Study Using an In Vivo Rabbit Ear Model. [R] . Seth, A. K., Geringer, M. R., Gurjala, A. N., 2012

机译：用临床伤口护理策略治疗铜绿假单胞菌生物膜感染伤口：使用体内兔耳模型的定量研究。

Clinically Relevant Epithelial Lining Fluid Concentrations of Meropenem with Ciprofloxacin Provide Synergistic Killing and Resistance Suppression of Hypermutable Pseudomonas aeruginosa in a Dynamic Biofilm Model

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