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Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis

机译：叔胺吡唑酮及其盐作为突变体超氧化物歧化酶1依赖性蛋白质聚集的抑制剂，用于治疗肌营养的侧刀

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Yinan Zhang; Kevin Tianmeng Zhao; Susan G. Fox; Jinho Kim; Donald R. Kirsch; Robert J. Ferrante; Richard I. Morimoto; Richard B. Silverman;
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1. Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis [J] . Zhang Yinan, Zhao Kevin Tianmeng, Fox Susan G., Journal of Medicinal Chemistry . 2015,第15期

机译：叔胺吡唑啉酮及其盐作为突变型超氧化物歧化酶1依赖性蛋白聚集的抑制剂，用于治疗肌萎缩性侧索硬化症
2. ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: Potential application for the treatment of amyotrophic lateral sclerosis [J] . Chen T., Benmohamed R., Kim J., Journal of Medicinal Chemistry . 2012,第1期

机译：ADME指导设计和合成芳基氧杂基吡唑啉酮衍生物，以阻止突变型超氧化物歧化酶1（SOD1）细胞毒性和蛋白质聚集：在治疗肌萎缩性侧索硬化症中的潜在应用
3. Arylazanylpyrazolone derivatives as inhibitors of mutant superoxide dismutase 1 dependent protein aggregation for the treatment of amyotrophic lateral sclerosis [J] . Zhang Y., Benmohamed R., Huang H., Journal of Medicinal Chemistry . 2013,第6期

机译：Arylazanylpyrazolone衍生物作为突变型超氧化物歧化酶1依赖性蛋白聚集的抑制剂，用于治疗肌萎缩性侧索硬化
4. Identification of Three Mutations in the Cu,Zn-Superoxide Dismutase (Cu,Zn-SOD) Gene with Familial Amyotrophic Lateral Sclerosis: Transduction of Human Cu,Zn-SOD into PC12 Cells by HIV-1 TAT Protein Basic Domain [C] . CHIH-MING CHOU, CHANG-JEN HUANG, CHWEN-MING SHIH, Asian Society for Mitochondrial Research and Medicine . 2005

机译：鉴定Cu，Zn-超氧化物歧化酶（Cu，Zn-SOD）基因的三种突变与家族性肌肌疏远硬化剂：HIV-1 TAT蛋白碱性结构域的转导，Zn-SOD进入PC12细胞
5. Arylsulfanyl Pyrazolones Block Mutant SOD1 Aggregation and have Potential Application for the Treatment of Amyotrophic Lateral Sclerosis. [D] . Chen, Tian. 2011

机译：芳硫基吡唑啉酮可阻止突变型SOD1聚集，并可能在肌萎缩性侧索硬化症的治疗中应用。
6. Tertiary amine pyrazolones and their salts as inhibitors of mutant superoxide dismutase 1-dependent protein aggregation for the treatment of amyotrophic lateral sclerosis [O] . Yinan Zhang, Kevin Tianmeng Zhao, Susan G. Fox, -1

机译：叔胺吡唑啉酮及其盐类作为突变型超氧化物歧化酶1依赖性蛋白聚集的抑制剂用于治疗肌萎缩性侧索硬化症
7. Superoxide Dismutase 1 (SOD1)-Derived Peptide Inhibits Amyloid Aggregation of Familial Amyotrophic Lateral Sclerosis SOD1 Mutants [O] . -1

机译：超氧化物歧化酶1（SOD1）相移的肽抑制家族肌萎缩侧硬化剂SOD1突变体的淀粉样蛋白聚集

Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis

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