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Different Effects on Human Topoisomerase I by Minor Groove and Intercalated Deoxyguanosine Adducts Derived from Two Polycyclic Aromatic Hydrocarbon Diol Epoxides at or Near a Normal Cleavage Site

机译：在正常切割位点或附近衍生自正常切割位点或附近的两种多环芳烃二醇环氧化物的较小凹槽和插入的脱氧胍酶加合物的不同效果

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Yves Pommier; Glenda Kohlhagen; Gary S. Laco; Heiko Kroth; Jane M. Sayer; Donald M. Jerina;
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年度 2002
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1. Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N-2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement [J] . Zhang N, Lin C, Huang XW, Journal of Molecular Biology . 2005,第4期

机译：CpG序列中C5处胞嘧啶的甲基化会导致DNA中苯并[a] py二醇环氧-N-2-鸟嘌呤加合物的构象转换，从小沟比对到碱基置换插入
2. Mispairing of a Site Specific Major Groove (2S,3S)-N~6-(2,3,4-Trihydroxybutyl)-2'-deoxyadenosyl DNA Adduct of Butadiene Diol Epoxide with Deoxyguanosine:Formation of a dA(anti) centre dot dG(anti) Pairing Interaction [J] . Tandace A.Scholdberg, Lubomir V.Nechev, W.Keither Merritt, Chemical research in toxicology . 2005,第2期

机译：特定位置的主要沟槽（2S，3S）-N〜6-（2,3,4-三羟基丁基）-2'-脱氧腺苷DNA与丁二烯二醇环氧与脱氧鸟苷的配对错误：dA（anti）中心点dG的形成（反）配对互动
3. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove [J] . Feng B, Gorin A, Kolbanovskiy A, Biochemistry . 1997,第45期

机译：与DNA双链体中缺失位点相对的（-）-反-[-]-[BP] dG加合物的溶液构象：共价连接的苯并[a]]插入螺旋中，修饰的脱氧鸟嘌呤碱基移入小沟中
4. EFFECTS AND MECHANISM OF ACTION OF NAPHTHALENE, A PETROLEUM-DERIVED POLYCYCLIC AROMATIC HYDROCARBON, ON BLACK PIGMENT DISPERSION IN THE SALT MARSH FIDDLER CRAB, UCA PUGILATOR. [D] . STAUB, GREGORY CYRIL. 1983

机译：萘（一种石油衍生的多环芳烃）对盐沼滤料蟹，UCA粉碎机中黑色素弥散的影响及其作用机理。
5. Benzoapyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages [O] . Yves Pommier, Glenda Kohlhagen, Philippe Pourquier, 2000

机译：DNA中的苯并a py二醇环氧加合物是正常拓扑异构酶I切割位点的有效抑制剂是其他拓扑异构酶I切割的有力诱导剂
6. Benzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages [O] . Pommier, Yves, Kohlhagen, Glenda, Pourquier, Philippe, 2000

机译：DNA中的苯并[a] py二醇环氧加合物是正常拓扑异构酶I切割位点的有效抑制剂，是其他拓扑异构酶I切割的有力诱导剂
7. NMR solution structures of adducts derived from the binding of polycyclic aromatic diol epoxides to DNA [R] . Cosman, M. , Patel, D. J. , Hingerty, B. E. , 1995

机译：衍生自多环芳族二醇环氧化物与DNa结合的加合物的NmR溶液结构

Different Effects on Human Topoisomerase I by Minor Groove and Intercalated Deoxyguanosine Adducts Derived from Two Polycyclic Aromatic Hydrocarbon Diol Epoxides at or Near a Normal Cleavage Site

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