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Adamantane derivatives having heterocyclic and monoterpenoid residues as potent Tdp1 inhibitors

机译：具有杂环和单萜类残留物作为有效的TDP1抑制剂的金刚烷衍生物

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Aldar Munkuev; Alexandra Zakharenko; Evgeniy Suslov; Arina Chepanova; Konstantin Volcho; Nariman Salakhutdinov; Olga Lavrik;
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1. Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments [J] . Mozhaitsev Evgcnii S., Zakharenko Alexandra L., Suslov Evgeniy V, Anti-cancer agents in medicinal chemistry . 2019,第4期

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2. Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors [J] . Olga Zakharova, Olga Luzina, Alexandra Zakharenko, Bioorganic and medicinal chemistry . 2018,第15期

机译：芳基和亚赤素呋喃酮衍生物的合成与评价，如高效的TDP1抑制剂
3. Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes [J] . Pagire Suvarna H., Pagire Haushabhau S., Lee Gwi Bin, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2015,第Null期

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4. Molecular Docking Analysis of Podophyllotoxin Derivatives in Sulawesi Propolis as Potent Inhibitors of Protein Kinases [C] . Darin Flamandita, Kenny Lischer, Diah Kartika Pratami, International Symposium on Sustainable and Clean Energy;International Conference on Quality in Research . 2020

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5. A Heck-Based Approach to the Synthesis of Anacardic Acids and an Exploration of Its Derivatives as Small-Molecule Inhibitors of the Sumo E1 Enzyme and Aminoalkylation of Adamantanes Using Dual Photoredox-Hat Catalysis [D] . Weigel, William Kenneth, III. 2020

机译：一种基于Heck的嗜酸性酸合成的方法和衍生物作为Sumo E1酶的小分子抑制剂的探索，使用双光毒毒帽催化与氨烷烷的氨基烷基化物
6. Design Synthesis and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1 [O] . Irina V. Il’ina, Nadezhda S. Dyrkheeva, Alexandra L. Zakharenko, 2020

机译：TDP1新型3 - Carene-restive抑制剂新类别的设计合成和生物学研究
7. Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments [O] . Aldar A. Munkuev, Evgenii S. Mozhaitsev, Arina A. Chepanova, 2021

机译：基于金刚烷的新型TDP1抑制剂通过杂环片与单萜部分连接

Adamantane derivatives having heterocyclic and monoterpenoid residues as potent Tdp1 inhibitors

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