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Selection of Small Molecules that Bind to and Activate the Insulin Receptor from a DNA-Encoded Library of Natural Products

机译：从DNA编码的天然产品文库中选择结合和激活胰岛素受体的小分子

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Jia Xie; Shuyue Wang; Peixiang Ma; Fei Ma; Jie Li; Wei Wang; Fengping Lu; Huan Xiong; Yuang Gu; Shuning Zhang; Hongtao Xu; Guang Yang; Richard A. Lerner;
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1. Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor [J] . Wu Zining, Graybill Todd L., Zeng Xin, ACS combinatorial science . 2015,第12期

机译：基于细胞的选择扩展了DNA编码的小分子文库技术对细胞表面药物靶标的实用性：NK3速激肽受体新型拮抗剂的鉴定
2. Selective Discovery of GPCR Ligands within DNA-Encoded Chemical Libraries Derived from Natural Products: A Case Study on Antagonists of Angiotensin II Type I Receptor [J] . Liang Qi, He Jianyu, Zhao Xue, Journal of Medicinal Chemistry . 2021,第7期

机译：来自天然产品的DNA编码化学文库中的GPCR配体的选择性发现：血管紧张素II型I受体拮抗剂的案例研究
3. Selection of affibody molecules to the ligand-binding site of the insulin-like growth factor-1 receptor [J] . Jingjing Li, Emma Lundberg, Erik Vernet, Biotechnology and Applied Biochemistry . 2010,第Pta2期

机译：亲和分子对胰岛素样生长因子-1受体配体结合位点的选择
4. Development of a mAb Binding a Conformational Epitope on Human and Rodent Insulin Receptor Using a Naive Antibody Yeast Display Library [C] . Morten Gronbech Rasch, Rita Slaaby, Niels Blume Protein Engineering Summit. . 2018

机译：使用Naive抗体酵母显示文库在人和啮齿动物胰岛素受体上结合构象表位的MAB
5. mRNA Display selection of a novel activated leukocyte cell adhesion molecule (ALCAM) binding protein from a modified combinatorial protein library based on the tenth domain of human fibronection III (10FnIII). [D] . Park, Ann Nahhyun. 2015

机译：从基于人纤维蛋白III（10FnIII）的第十个域的修饰的组合蛋白文库中选择新型激活白细胞粘附分子（ALCAM）结合蛋白的mRNA显示。
6. Selection of Small Molecules that Bind to and Activate the Insulin Receptor from a DNA-Encoded Library of Natural Products [O] . Jia Xie, Shuyue Wang, Peixiang Ma, 2020

机译：从DNA编码的天然产品文库中选择结合和激活胰岛素受体的小分子
7. A Screen for Dual-protection Molecules from a Natural Product Library against Neuronal Cell Death and Microglial Cell Activation [O] . Ju-Sik Min, Dong-Seok Lee 2015

机译：来自天然产物文库对神经元细胞死亡和小胶质细胞活化的双保护分子的筛网

Selection of Small Molecules that Bind to and Activate the Insulin Receptor from a DNA-Encoded Library of Natural Products

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