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Faculty Opinions recommendation of Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial.

机译：教师意见的建议在健康的成人和2型糖尿病患者中与volxibat的安全性，耐受性和药效动性的安全性，耐受性和药效动性和药效动性，患有型糖尿病患者：随机安慰剂对照试验。

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Carlos Aguilar-Salinas;
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1. Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial [J] . Renger G. Tiessen, Ciara A. Kennedy, Bradley T. Keller, BMC Gastroenterology . 2018,第1期

机译：在健康成年人和2型糖尿病患者中使用Volixibat抑制根尖钠依赖性胆汁酸转运蛋白的安全性，耐受性和药效学：一项随机安慰剂对照试验
2. Volixibat, a minimally absorbed, oral, apical sodium-dependent bile acid transporter (ASBT) inhibitor, increases bile acid excretion, reduces serum lipids, is safe and tolerable in overweight and obese subjects, a population characteristic of NASH [J] . Palmer Melissa, Jennings Lee, Silberg Debra, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2016,第S1期

机译：Volxibat，一种微小的吸收口服，顶端依赖性胆汁酸转运蛋白（ASBT）抑制剂，增加胆汁酸排泄，减少血清脂质，在超重和肥胖的主题中是安全可耐受的，纳什的人口特征
3. Apical Sodium-Dependent Bile Acid Transporter Inhibition with Volixibat Impacts Metabolic and Physiologic Parameters Associated with the Development of Nonalcoholic Steatohepatitis (NASH) in a High-Fat Diet-Fed Mouse Model [J] . Wilkins-Port Cynthia, McNulty John, Kleemann Robert, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2017,第Suppla1期

机译：具有volxibat的顶端依赖性胆汁酸转运蛋白抑制作用与高脂肪饮食喂养小鼠模型中非酒精脂肪骨膜炎（NASH）的发育相关的代谢和生理参数
4. Inhibition and substrate requirements of human apical sodium-dependent bile acid transporter (ASBT) and its potential as a prodrug target. [D] . Zheng, Xiaowan. 2010

机译：人类根尖钠依赖性胆汁酸转运蛋白（ASBT）的抑制和底物要求及其作为前药靶标的潜力。
5. Safety tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial [O] . Renger G. Tiessen, Ciara A. Kennedy, Bradley T. Keller, 2018

机译：在健康成年人和2型糖尿病患者中使用Volixibat抑制根尖钠依赖性胆汁酸转运蛋白的安全性耐受性和药效学：一项随机安慰剂对照试验
6. Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial [O] . Renger G. Tiessen, Ciara A. Kennedy, Bradley T. Keller, 2018

机译：含钠依赖性胆汁酸转运蛋白的安全性，耐受性和药效学与健康成人葡萄球菌和2型糖尿病患者：随机安慰剂对照试验

Faculty Opinions recommendation of Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial.

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