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Replacing the Factor VIII C1 Domain with a Second C2 Domain Reduces Factor VIII Stability and Affinity for Factor IXa

机译：用第二C2域替换因子VIII C1域，减少因子VIII稳定性和因子IXA的亲和力

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Hironao Wakabayashi; Philip J. Fay;
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1. Replacing the Factor VIII C1 Domain with a Second C2 Domain Reduces Factor VIII Stability and Affinity for Factor IXa [J] . Hironao Wakabayashi, Philip Fay The Journal of biological chemistry . 2013,第43期

机译：用第二C2域替换因子VIII C1域，减少因子VIII稳定性和因子IXA的亲和力
2. A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function. [J] . Lu J, Pipe SW, Miao H, Blood: The Journal of the American Society of Hematology . 2011,第11期

机译：因子VIII C1结构域上的膜相互作用表面与C2结构域协同发挥辅助因子功能。
3. Relationship between the Binding Sites for von Willebrand Factor, Phospholipid, and Human Factor VIII C2 Inhibitor Alloantibodies within the Factor VIII C2 Domain [J] . Keiji Nogami, Midori Shima, John C. Giddings, International Journal of Hematology . 2007,第4期

机译：因子VIII C2结构域内von Willebrand因子，磷脂和人类因子VIII C2抑制剂同种抗体的结合位点之间的关系
4. Differences in structural dynamics of Factor VIII and Lactadherin C2 domains in relation to membrane binding employing DXMS analysis. [C] . Dennis P. Pantazatos, Chris Gessner, G. E. Gilbert, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：与膜结合的因子VIII和乳酸素C2结构域的结构动态的差异与DXMS分析相关。
5. Role of macromolecular interactions in the pharmacokinetics and immunogenicity of recombinant human factor VIII and factor VIII-lipid complex [D] . Pisal, Dipak Shriram 2012

机译：大分子相互作用在重组人VIII因子和VIII因子-脂质复合物的药代动力学和免疫原性中的作用
6. Replacing the Factor VIII C1 Domain with a Second C2 Domain Reduces Factor VIII Stability and Affinity for Factor IXa [O] . Hironao Wakabayashi, Philip J. Fay 2013

机译：用第二个C2域替换因子VIII C1域会降低因子IXa的因子VIII稳定性和亲和力
7. A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor [O] . Jacquemin Marc, Lavendhomme R, Benhida Abdellah, 2000

机译：轻度/中度血友病的新病因A：分散在因子VIII C1域中的突变减少了因子VIII与von Willebrand因子的结合
8. Influence of Factor VIII/von Willebrand Factor Protein (F VIII/vWF) and F VIII/vWF-Poor Cryoprecipitate on Post-Ischemic Microvascular Reperfusion in the Central Nervous System [R] . Hallenbeck, J. M., Furlow, T. W., Gralnick, H. R. 1980

机译：因子VIII / von Willebrand因子蛋白（F VIII / vWF）和F VIII / vWF-差冷沉淀物对中枢神经系统缺血后微血管再灌注的影响

Replacing the Factor VIII C1 Domain with a Second C2 Domain Reduces Factor VIII Stability and Affinity for Factor IXa

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