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Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR

机译：芘是一种新的组成型和过滤烷受体（汽车）活化剂，并通过汽车引起肝毒性

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Xiao-Jie Zhang; Zhe Shi; Jing-Xi Lyv; Xuyan He; Neal A. Englert; Shu-Yun Zhang;
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1. Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR [J] . Zhang Xiao-Jie, Shi Zhe, Lyv Jing-Xi, Toxicological sciences: An official journal of the Society of Toxicology . 2015,第2期

机译：yr是新型组成型雄激素受体（CAR）活化剂，可通过CAR引起肝毒性
2. Phenanthrene, but not its isomer anthracene, effectively activates both human and mouse nuclear receptor constitutive androstane receptor (CAR) and induces hepatotoxicity in mice [J] . Yang Han, Shi Zhe, Wang Xiao-Xiao, Toxicology and Applied Pharmacology . 2019,第期

机译：菲，但不是其异构体蒽，有效地活化了人和小鼠核受体构成androstane受体（轿车）并诱导小鼠肝毒性
3. Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital [J] . Schraplau Anne, Schewe Bettina, Neuschaefer-Rube Frank, Toxicology: An International Journal Concerned with the Effects of Chemicals on Living Systems . 2015,第3期

机译：通过通过苯并[a]芘和苯丙乙烯和苯丙乙烯的组成型和rostane受体（汽车，NR1i3）和芳基氢碳受体互感增强肝细胞中的甲状腺激素分解
4. Direct activation of Constitutive Androstane Receptor by Phthalates [C] . Haishan LI, Wenchao AI, Hui HAN, International Conference on Biological Engineering and Pharmacy . 2017

机译：通过邻苯二甲酸酯直接激活组成型和rostane受体
5. Metabolism-Based Alterations of Constitutive Androstane Receptor (CAR) Activity and Downstream Effects [D] . Mackowiak, Bryan. 2019

机译：基于代谢的组成雌激素受体（CAR）活性和下游效应的改变
6. Induction of Mouse UDP-Glucuronosyltransferase mRNA Expression in Liver and Intestine by Activators of Aryl-Hydrocarbon Receptor Constitutive Androstane Receptor Pregnane X Receptor Peroxisome Proliferator-Activated Receptor α and Nuclear Factor Erythroid 2-Related Factor 2 [O] . David B. Buckley, Curtis D. Klaassen -1

机译：小鼠肝脏中UDP-葡萄糖醛酸转移酶mRNA表达的诱导和肠道由芳烃受体活化剂组成型雄激素受体孕烷X受体过氧化物酶体增殖物激活受体α和核因子类红细胞2相关因子2
7. Induction of Mouse UDP-Glucuronosyltransferase mRNA Expression in Liver and Intestine by Activators of Aryl-Hydrocarbon Receptor, Constitutive Androstane Receptor, Pregnane X Receptor, Peroxisome Proliferator-Activated Receptor α, and Nuclear Factor Erythroid 2-Related Factor 2 [O] . Buckley, David B., Klaassen, Curtis D. 2009

机译：小鼠肝脏中UDP-葡萄糖醛酸转移酶mRNA表达的诱导和肠道由芳烃受体活化剂组成型雄激素受体，孕烷X受体，过氧化物酶体增殖物激活受体α和核因子类红细胞2相关因子2
8. Endosulfan-alpha Induces CYP26 and CYP3A4 by Activating the Pregnane X Receptor But Not the Constitutive Androstane Receptor [R] . Casabar, R. C. 2006

机译：硫丹-α通过激活孕烷X受体而不是组成型雄甾烷受体诱导CYp26和CYp3a4

Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR

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