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Hydroxylation andN-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms

机译：人的细胞色素P450s及其常见发生多态性Ifosfamide和氘代甲基甲基化的羟基化和氯甲基化及其常见多态性

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Diane M. Calinski; Haoming Zhang; Susan Ludeman; M. Eileen Dolan; Paul F. Hollenberg;
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1. Hydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms [J] . Diane M. Calinski, Haoming Zhang, Susan Ludeman, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2015,第7期

机译：细胞色素P450对异环磷酰胺和氘代异环磷酰胺的羟化和N-脱氯乙基化作用及其常见的多态性
2. Enantioselective metabolism and cytotoxicity of R-Ifosfamide and S-Ifosfamide by tumor cell-expressed cytochromes P450. [J] . Chen CS, Jounaidi Y, Waxman DJ Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2005,第9期

机译：肿瘤细胞表达的细胞色素P450对R-异环磷酰胺和S-异环磷酰胺的对映选择性代谢和细胞毒性。
3. Effects of the selected cytochrome P450 oxidoreductase genetic polymorphisms on cytochrome P450 2B6 activity as measured by bupropion hydroxylation [J] . Lv Jinfeng, Hu Lei, Zhuo Wei, Pharmacogenetics and genomics . 2016,第2期

机译：通过安非他酮羟化测定，选定的细胞色素P450氧化还原酶基因多态性对细胞色素P450 2B6活性的影响
4. Re-engineering cytochrome P450 2B 11 dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide [C] . Ling Sun, Chong S.Chen, David J.Waxman, 第四届国际分子模拟与信息技术应用学术会议（The 4th International Conference of Molecular Simulations and Applied Informatics Technologies）论文集 . 2008

机译：重新设计细胞色素P450 2B 11 dH，以增强几种底物的代谢，包括抗癌前药环磷酰胺和异环磷酰胺
5. Human pulmonary biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and impact of genetic polymorphisms on cytochrome P450 1A1-related activities in human lung. [D] . Smith, Graeme Bradford James. 2001

机译：4-（甲基亚硝胺基）-1-（3-吡啶基）-1-丁酮的人肺生物转化以及遗传多态性对人肺中细胞色素P450 1A1相关活性的影响。
6. Hydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms [O] . Diane M. Calinski, Haoming Zhang, Susan Ludeman, -1

机译：细胞色素P450对异环磷酰胺和氘代异环磷酰胺的羟化和N-脱氯乙基化作用及其常见的多态性
7. Debrisoquine-type polymorphism of drug oxidation: purification from human liver of a cytochrome P450 isozyme with high activity for bufuralol hydroxylation [O] . Gut J., Gasser R., Dayer P., 1984

机译：药物氧化的异百喹啉型多态性：从人肝中纯化具有高活性的丁三醇羟基化作用的细胞色素P450同工酶

Hydroxylation andN-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms

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