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Combinatorial Screening and Rational Optimization for Hybridization to Folded Hepatitis C Virus RNA of Oligonucleotides with Biological Antisense Activity

机译：与生物反义活动寡核苷酸折叠丙型肝炎病毒RNA的组合筛选和合理优化

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Walt F. Lima; Vickie Brown-Driver; Maureen Fox; Ronnie Hanecak; Thomas W. Bruice;
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年度 1997
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1. Control of complexity constraints on combinatorial screening for preferred oligonucleotide hybridization sites on structured RNA. [J] . Bruice TW, Lima WF Biochemistry . 1997,第16期

机译：控制复杂性限制条件，进行组合筛选，筛选结构化RNA上的首选寡核苷酸杂交位点。
2. POTENT ANTISENSE OLIGONUCLEOTIDES TO THE HUMAN MULTIDRUG RESISTANCE-1 MRNA ARE RATIONALLY SELECTED BY MAPPING RNA-ACCESSIBLE SITES WITH OLIGONUCLEOTIDE LIBRARIES [J] . Ho SP, Britton DHO, Stone BA, Nucleic Acids Research . 1996,第10期

机译：通过将RNA易位位点与寡核苷酸文库配对，可以合理选择对人类多药耐药性1 MRNA的强效反义寡核苷酸
3. Differential Pulse Voltammetric Detection of Hepatitis C Virus 1a Oligonucleotide Chain by a Label-Free Electrochemical DNA Hybridization Biosensor Using Consensus Sequence of Hepatitis C Virus 1a Probe on the Pencil Graphite Electrode [J] . Pournaghi-Azar MH, Ahour F, Hejazi MS Electroanalysis . 2009,第16期

机译：使用标记电化学DNA杂交生物传感器在铅笔石墨电极上使用丙型肝炎病毒1A探针的共识序列，鉴别脉冲伏安检测甲型肝炎病毒1A寡核苷酸链寡核苷酸链
4. Enhancing antisense oligonucleotide efficacy in vivo by improving both antisense design using RNAse H accessibility mapping and sustained hippocampal delivery using biodegradeabile microspheres [C] . A.Islam, K.S.J.thompson, S.Akhtar, International symposium on controlled release of bioactive materials;Consumer and diversified products conference . 2000

机译：通过改善使用RNAse H可及性作图的反义设计和使用可生物降解的微球体持续进行海马递送来增强体内反义寡核苷酸的功效
5. Inhibition of duck hepatitis B virus by antisense poly-2'-O-(2,4-dinitrophenyl)-oligoribonucleotide. [D] . Xin, Wei. 1999

机译：反义聚-2'-O-（2,4-二硝基苯基）-寡核糖核苷酸对鸭乙型肝炎病毒的抑制作用。
6. Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries. [O] . S P Ho, D H Britton, B A Stone, 1996

机译：通过将具有寡核苷酸文库的RNA可及位点作图可以合理地选择针对人类多药耐药性1 mRNA的有效反义寡核苷酸。
7. Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries. [O] . Ho, S P, Britton, D H, Stone, B A, 1996

机译：通过将具有寡核苷酸文库的RNA可及位点作图，可以合理地选择针对人类多药耐药性1 mRNA的有效反义寡核苷酸。

Combinatorial Screening and Rational Optimization for Hybridization to Folded Hepatitis C Virus RNA of Oligonucleotides with Biological Antisense Activity

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