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Non‐additive effect on thrombin generation when a plasma‐derived factor VIII/von Willebrand factor (FVIII/VWF) is combined with emicizumab in vitro

机译：当等离子体衍生因子VIII / von Willebrand因子（FVIII / VWF）与体外eMicizumab与Emicizumab相结合时对凝血酶产生的非添加效应

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María Isabel Bravo; Aida Raventós; Alba Pérez; Montserrat Costa; Todd Willis;
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1. An Open-Label Extension Study to Assess the Long-Term Efficacy and Safety of a Plasma-Derived von Willebrand Factor (VWF)/Factor VIII (FVIII) Concentrate in Patients with von Willebrand Disease (SWIFT-VWDext Study) [J] . Toshko Lissitchkov, Anna Klukowska, Evgeny Buevich, Journal of Blood Medicine . 2020,第1期

机译：开放标签扩展性研究，以评估血浆衍生的von Willebrand因子（VWF）/因子VIII（FVIII）浓缩物的长期疗效和安全性（SWIFT-VWDEXT研究）
2. THE COMBINATION OF PLASMA-DERIVED FVIII/VWF WITH EMICIZUMAB HAS NON-ADDITIVE EFFECTS ON THROMBIN GENERATION ASSAY INDEPENDENTLY OF THE PRESENCE OF INHIBITORS IN HEMOPHILIA A PLASMA [J] . Bravo M. I., Raventos A., Perez A., Archives of disease in childhood . 2019,第Suppla1期

机译：血浆衍生的FVIII / vWF与Emicizumab的组合在血友病血浆中的抑制剂存在的情况下具有对凝血酶产生测定的非添加性效应
3. Von Willebrand Factor (VWF) Propeptide and Factor VIII (FVIII) Levels Identify the Contribution of Decreased Synthesis and/or Increased Clearance Mechanisms in the Pathogenesis of Type 1 Von Willebrand Disease (VWD) in the Zimmerman Program [J] . Haberichter Sandra L., Christopherson Pamela A., Flood Veronica H., Blood: The Journal of the American Society of Hematology . 2016,第22期

机译：冯·威勒布兰德（VWF）肽和因子VIII（FVIII）水平在Zimmerman计划中确定了1型冯·威勒布兰德病（VWD）发病机理中合成减少和/或清除机制增加的贡献
4. IMMUNATE S/D - A new Factor VIII - von-Willebrand Factor Complex Concentrate [C] . P.L. Turecek, W. Schonhofer, T.R. Kreil, Hemophilie-Symposion . 2004

机译：免疫S / D - 一种新因子VIII - von-Willebrand系数复合浓缩物
5. The effect of biomechanical and biochemical regulators on the expression of Factor VIII and von Willebrand Factor in endothelial cells [D] . Leonard, Jacqueline Marianna Morello. 2016

机译：生物力学和生化调节剂对内皮细胞中VIII因子和von Willebrand因子表达的影响
6. An Open-Label Extension Study to Assess the Long-Term Efficacy and Safety of a Plasma-Derived von Willebrand Factor (VWF)/Factor VIII (FVIII) Concentrate in Patients with von Willebrand Disease (SWIFT-VWDext Study) [O] . Toshko Lissitchkov, Anna Klukowska, Evgeny Buevich, 2020

机译：开放标签扩展性研究以评估血浆衍生的von Willebrand因子（VWF）/因子VIII（FVIII）浓缩物的长期疗效和安全性（SWIFT-VWDEXT研究）
7. Efficacy, Safety and Pharmacokinetic Results of a Phase III, Open-Label, Multicenter Study with a Plasma-Derived Von Willebrand Factor (VWF)/Factor VIII (FVIII) Concentrate in Pediatric Patients [O] . Claudia Djambas Khayat, Genadi Iosava, Irina Romashevskaya, 2021

机译：III期，开放标签，多中心研究的疗效，安全性和药代动力学结果与血浆衍生的von Willebrand因子（VWF）/因子VIII（FVIII）浓缩在儿科患者中
8. Influence of Factor VIII/von Willebrand Factor Protein (F VIII/vWF) and F VIII/vWF-Poor Cryoprecipitate on Post-Ischemic Microvascular Reperfusion in the Central Nervous System [R] . Hallenbeck, J. M., Furlow, T. W., Gralnick, H. R. 1980

机译：因子VIII / von Willebrand因子蛋白（F VIII / vWF）和F VIII / vWF-差冷沉淀物对中枢神经系统缺血后微血管再灌注的影响

Non‐additive effect on thrombin generation when a plasma‐derived factor VIII/von Willebrand factor (FVIII/VWF) is combined with emicizumab in vitro

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