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Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

机译：将PI3K抑制剂与PARP抑制剂组合为BRCA1相关的乳腺癌提供了有效的治疗方法

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Ashish Juvekar; Laura N. Burga; Hai Hu; Elaine P. Lunsford; Yasir H. Ibrahim; Judith Balmañà; Anbazhagan Rajendran; Antonella Papa; Katherine Spencer; Costas A. Lyssiotis; Caterina Nardella; Pier Paolo Pandolfi; José Baselga; Ralph Scully; John M. Asara; Lewis C. Cantley; Gerburg M. Wulf;
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1. Combined treatment with PI3K inhibitor BKM120 and PARP inhibitor olaparib is effective in inhibiting the gastric cancer cells with ARID1A deficiency [J] . Yang Lin, Yang Guanghai, Ding Yingjun, Oncology reports . 2018,第1期

机译：用PI3K抑制剂BKM120和PARP抑制剂Olaparib的组合治疗有效抑制ARID1A缺乏的胃癌细胞
2. Combining PI3K and PARP inhibitors for breast and ovarian cancer treatment [J] . Condorelli R., Andre F. Annals of oncology: official journal of the European Society for Medical Oncology . 2017,第6期

机译：结合PI3K和PARP抑制剂对乳腺癌和卵巢癌治疗
3. An Effective Epigenetic-PARP Inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA Mutations [J] . Pulliam Nicholas, Fang Fang, Ozes Ali R., Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第13期

机译：乳腺癌和卵巢癌无关的有效表观遗传 - PARP抑制剂组合治疗无关BRCA突变
4. A mathematical cancer model with BCG immunotherapy combined with immune checkpoints inhibitors: An optimal control approach [C] . Evren Hincal, Farouk Tijjani Saad, Isa Abdullahi Baba International Conference on Analysis and Applied Mathematics . 2018

机译：具有BCG免疫疗法的数学癌模型与免疫检查点抑制剂相结合：最佳控制方法
5. Smart Brachytherapy Spacers for Combined Chemo-Radiation Therapy: Local Delivery of Nanoparticles, Chemotherapeutics, and Molecular Inhibitors for Cancer Treatment [D] . Belz, Jodi Elizabeth. 2017

机译：用于组合化疗疗法的智能近距离放射治疗：纳米粒子，化学治疗剂和分子抑制剂的局部递送癌症治疗
6. Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer [O] . Ashish Juvekar, Laura N. Burga, Hai Hu, -1

机译：将PI3K抑制剂与PARP抑制剂组合为BRCA1相关的乳腺癌提供了有效的治疗方法
7. An Effective Epigenetic-PARP Inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA Mutations [O] . Nicholas Pulliam, Fang Fang, Ali R. Ozes, 2018

机译：乳腺癌和卵巢癌无关的有效表观遗传 - PARP抑制剂组合治疗无关BRCA突变
8. Treatment of BRCA1/2 Hereditary Breast Cancer and Sporadic Breast Cancer with Poly(ADP-ribose) PARP-1 Inhibitors and Chemotherapy [R] . DeSoto, J. A. 2008

机译：聚（aDp-核糖）paRp-1抑制剂和化疗治疗BRCa1 / 2遗传性乳腺癌和散发性乳腺癌

Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

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