Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers

摘要

By employment of a pre-designed molecular building block [(pzTp)Fe(CN)3], one cyano-bridged trinuclear complex [MnMe4TACD][(pzTp)Fe(CN)3]2(H2O)16 1, [pzTp = tetrakis(pyrazoly)borate, Me4TACD = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane] and two 1D chain-like coordination polymers {[(pzTp)Fe(CN)3]2[M(Bim)2](H2O)2}n [M = Cu(II) for 2 and Mn(II) for 3, Bim = bis(1-imidazolyl)methane] were synthesized by making use of different nitrogen-containing organic linkers. Furthermore, in vitro cytotoxicity of compounds 1–3 was studied against four human liver cancer cells (HepG2, Bel-7402, SMMC7721, and MHCC97) via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium (MTT) assay experiments.