Biologically active natural products often contain particularly challenging structural features andudfunctionalities in terms of synthesis. Perhaps the greatest difficulties are those caused by issues ofudstereochemistry. A useful strategy for synthesizing such molecules is to devise methods of bond formationudthat provide opportunities for using enantioselective catalysis. In using this tactic, the desire for a particularudtarget structure ultimately drives the development of catalytic methods. New enantioselective catalyticudmethods contribute to a greater fundamental understanding of how bonds can be constructed and lead to valuable synthetic technologies that are useful for a variety of applications.
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