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Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer

机译：缺氧激活的前药Th-302靶向的选择性肿瘤缺氧抑制癌症的临床前模型中的肿瘤生长

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Jessica D. Sun; Qian Liu; Jingli Wang; Dharmendra Ahluwalia; Damien Ferraro; Yan Wang; Jian-Xin Duan; W. Steve Ammons; John G. Curd; Mark D. Matteucci; Charles P. Hart;
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1. 缺氧激活前药evofosfamide(TH-302)在体内和体外对鼻咽癌的疗效 [J] . Yan Huang, Ying Tian, Yuanyuan Zhao, 癌症（英文版） . 2018,第012期
2. Selective tumor hypoxia targeting by hypoxia-activated prodrug TH-302 inhibits tumor growth in preclinical models of cancer. [J] . Jessica D Sun, Qian Liu, Jingli Wang, Clinical cancer research: an official journal of the American Association for Cancer Research . 2012,第3期

机译：在癌症的临床前模型中，通过低氧激活的前药TH-302进行的选择性肿瘤低氧靶向抑制了肿瘤的生长。
3. Combination treatment with hypoxia-activated prodrug evofosfamide (TH-302) and mTOR inhibitors results in enhanced antitumor efficacy in preclinical renal cell carcinoma models [J] . Jessica D Sun, Dharmendra Ahluwalia, Qian Liu, American Journal of Cancer Research . 2015,第7期

机译：缺氧激活前药evofosfamide（TH-302）和mTOR抑制剂的联合治疗可增强临床前肾细胞癌模型的抗肿瘤功效
4. Combination treatment with hypoxia-activated prodrug evofosfamide (TH-302) and mTOR inhibitors results in enhanced antitumor efficacy in preclinical renal cell carcinoma models [J] . Jessica D Sun, Dharmendra Ahluwalia, Qian Liu, American Journal of Cancer Research . 2015,第7期

机译：缺氧激活前药evofosfamide（TH-302）和mTOR抑制剂的联合治疗可增强临床前肾细胞癌模型的抗肿瘤功效
5. α_vβ_3 INTEGRIN-TARGETED LIPOSOMES CONTAINING DOXORUBICIN INHIBIT TUMOR GROWTH AND ANGIOGENESIS IN A SYNGENEIC MURINE MELANOMA MODEL [C] . Charles A. Wartchow, Neal E. DeChene, S. Narasimhan Danthi, Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：含阿霉素抑制肿瘤生长和血管生成的α_vβ_3整合素靶向脂质体在共性鼠黑素瘤模型中的应用
6. Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor in solid tumors. [D] . Priceman, Saul Jonathan. 2009

机译：通过抑制实体瘤中的CSF-1受体靶向不同的浸润肿瘤的骨髓细胞。
7. Combination treatment with hypoxia-activated prodrug evofosfamide (TH-302) and mTOR inhibitors results in enhanced antitumor efficacy in preclinical renal cell carcinoma models [O] . Jessica D Sun, Dharmendra Ahluwalia, Qian Liu, 2015

机译：缺氧激活前药evofosfamide（TH-302）和mTOR抑制剂的联合治疗可增强临床前肾细胞癌模型的抗肿瘤功效
8. Selective Tumor Targeting by the Hypoxia-Activated Prodrug AQ4N Blocks Tumor Growth and Metastasis in Preclinical Models of Pancreatic Cancer [O] . Alshad S. Lalani, Susan E. Alters, Alvin Wong, 2007

机译：缺氧活化前药AQ4N靶向的选择性肿瘤嵌段胰腺癌临床前模型中的肿瘤生长和转移
9. Formulated Delivery of Enzyme/Prodrug and Cytokine Gene Therapy to Promote Immune Reduction of Treated and Remote Tumors in Mouse Models of Prostate Cancer [R] . Russell, P. J. , Khatri, A. , Husaini, Y. , 2007

机译：配方递送酶/前药和细胞因子基因治疗促进小鼠前列腺癌模型中治疗和远程肿瘤的免疫减少

Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer

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