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Incorporation of an Allogenic Cortical Bone Graft Following Arthrodesis of the First Metatarsophalangeal Joint in a Patient with Hallux Rigidus

机译:在Hallux刚性的患者中第一次跖蛋白关节关节阳性掺入同类皮质骨移植物

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摘要

Hallux rigidus is degenerative arthritis of the first metatarsophalangeal joint characterized by pain and stiffness in the joint with limitation of motion and functional impairment. Recently, bone grafts have been introduced in orthopedic procedures, namely osteosynthesis and arthrodesis. Allografts can induce bone formation, provide support for vascular and bone ingrowth and have a low risk of immunological rejection. A 52-year-old female patient with hallux rigidus underwent arthrodesis of the first metatarsophalangeal joint using Shark Screw® made of allogenic cortical bone. Corrective surgery was performed after 10 weeks, and a 5 × 3 mm large part of the Shark Screw® with the surrounding patient’s bone was removed. A histological evaluation revealed a vascularized graft with the newly formed compact lamellar bone fitting exactly to the cortical graft. The bone surface was lined by plump osteoblasts with osteoid production, and osteocytes were present in the lacunae. The arthrodesis of the first metatarsophalangeal joint using an allogenic cortical bone graft results in fast, primary bone healing without immunological rejection. This case suggests that the cortical allograft is a good and safe treatment option with an excellent graft incorporation into the host bone. However, as the literature evaluating the histology of different bone grafts is scarce, further high-level evidence studies with adequate sample sizes are needed to confirm our findings.
机译:Hallux Rigidus是第一个跖趾关节的退行性关节炎,其特征在于接头中的疼痛和刚度,其动作和功能障碍的限制。最近,骨移植物已在整形外科手术中引入,即骨骨合成和关节术。同种异体移植物可以诱导骨形成,为血管和骨骼产生的支持提供较低的免疫排斥的风险。一个52岁的女性患者,霍索刚性的静脉刚性接受第一位跖趾关节的关节,使用来自同种异体皮质骨制成的鲨鱼螺丝。矫正手术在10周后进行,并除去了鲨鱼螺钉的5×3毫米大部分鲨鱼螺丝。组织学评估揭示了一种血管化移植物,其与新形成的紧凑层骨合适完全缠绕在皮质移植物完全。骨表面由具有骨质制备的丰满成骨细胞衬里,并且在裂变中存在骨细胞。使用同种异体皮质骨移植物的第一个跖趾关节关节的关节术,导致快速,初级骨愈合而无需免疫抑制。这种情况表明皮质同种异体移植是一种良好和安全的治疗选择,具有优异的移植物掺入到宿主骨中。然而,由于评估不同骨移植的组织学的文献,因此需要具有足够样品尺寸的进一步高级别证据来确认我们的研究结果。

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