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Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells

机译：C9ORF72己核苷酸的表达重复膨胀导致形成RNA焦点和二肽重复蛋白，但不会影响神经元细胞中的自噬或蛋白酶体功能

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Stina Leskelä; Nadine Huber; Dorit Hoffmann; Hannah Rostalski; Anne M. Remes; Mari Takalo; Mikko Hiltunen; Annakaisa Haapasalo;
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1. Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells [J] . Leskela Stina, Huber Nadine, Hoffmann Dorit, Biochimica et biophysica acta. Molecular cell research . 2021,第7期

机译：C9ORF72己核苷酸的表达重复膨胀导致RNA焦谱和二肽重复蛋白的形成，但不会影响神经元细胞中的自噬或蛋白酶体功能
2. A 30-unit hexanucleotide repeat expansion in C9orf72 induces pathological lesions with dipeptide-repeat proteins and RNA foci, but not TDP-43 inclusions and clinical disease [J] . Gami Priya, Murray Christina, Schottlaender Lucia, Acta Neuropathologica . 2015,第4期

机译：C9orf72中30个单位的六核苷酸重复扩增可诱导具有二肽重复蛋白和RNA病灶的病理性病变，但不会诱导TDP-43夹杂物和临床疾病
3. Methylation of C9orf72 expansion reduces RNA foci formation and dipeptide-repeat proteins expression in cells [J] . Bauer Peter O. Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 2016,第1期

机译：C9orf72扩展的甲基化可减少细胞中RNA灶的形成和二肽重复蛋白的表达
4. Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (37): The formation of RNA foci in repeat expansion disorders is promoted in molecular crowding conditions [C] . Ye Teng, Hisae Tateishi-Karimata, Naoki Sugimoto 日本化学会春季年会講演予稿集 . 2018

机译：超越Watson-Crick双螺旋（37）的核酸化学：在分子中挤压条件下促进了重复膨胀障碍中的RNA焦点的形成
5. Transcriptional Inhibition of (GGGGCC) c9orf72 Hexanucleotide Repeat Expansion in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis [D] . Kim, Yujin E. 2019

机译：在额颞痴呆和肌萎缩性侧索硬化中（GGGGCC）c9orf72六核苷酸重复扩展的转录抑制。
6. Expression of human C9ORF72 hexanucleotide expansion reproduces RNA foci and dipeptide repeat proteins but not neurodegeneration in BAC transgenic mice [O] . Owen M. Peters, Gabriela Toro Cabrera, Helene Tran, -1

机译：在BAC转基因小鼠中人C9ORF72六核苷酸扩展的表达可复制RNA病灶和二肽重复蛋白但不会引起神经退行性变
7. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice [O] . Peters, Owen M., Toro Cabrera, Gabriela, Tran, Helene, 2015

机译：人类C9ORF72六核苷酸扩增再生BaC转基因小鼠中的RNa病灶和二肽重复蛋白但不是神经变性

Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells

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