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Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors

机译：靶向转录MCL-1对HER2扩增的乳腺癌敏化至HER2抑制剂

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Konstantinos V. Floros; Sheeba Jacob; Richard Kurupi; Carter K. Fairchild; Bin Hu; Madhavi Puchalapalli; Jennifer E. Koblinski; Mikhail G. Dozmorov; Sosipatros A. Boikos; Maurizio Scaltriti; Anthony C. Faber;
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1. Lapatinib, a Dual-Targeted Small Molecule Inhibitor of Egfr and Her2, in Her2-Amplified Breast Cancer: From Bench to Bedside [J] . Roger Y. Tsang, Saeed Sadeghi, Richard S. Finn Clinical Medicine Insights: Therapeutics . 2011,第3期

机译：拉帕替尼，Erfr和Her2的双重靶向小分子抑制剂，在Her2扩增乳腺癌中的作用：从实验台到床边
2. Combining AZD8931, a novel EGFR/HER2/HER3 signalling inhibitor, with AZD5363 limits AKT inhibitor induced feedback and enhances antitumour efficacy in HER2-amplified breast cancer models [J] . Claire Crafter, John P. Vincent, Eric Tang, International journal of oncology . 2015,第2期

机译：新型EGFR / HER2 / HER3信号抑制剂AZD8931与AZD5363的结合可限制AKT抑制剂诱导的反馈并增强在HER2扩增的乳腺癌模型中的抗肿瘤功效
3. Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells [J] . Eric Dietel, Alexander Brobeil, Claudia Tag, Oncogenesis. . 2018,第8期

机译：EGFR / HER2靶向药物的有效性受HER2扩增的乳腺癌细胞中PTPIP51下游相互作用转移的影响
4. Utilization of Flavonoid Compounds as HER2 Tyrosine Kinase Inhibitor in Breast Cancer Using Fragment-Based Drug Design [C] . Vincent Jonathan Fleming, Mutiara Saragih, Usman Sumo Friend Tambunan International Conference on Science and Technology . 2020

机译：使用碎片的药物设计在乳腺癌中用黄酮类化合物作为HER2酪氨酸激酶抑制剂
5. Design and Evaluation of Peptidomimetics and Peptidomimetics Drug Conjugates Targeting HER2 Overexpressing Cells in Breast and Lung Cancers [D] . Pallerla, Sandeep. 2017

机译：拟肽和拟肽药物结合物靶向乳腺癌和肺癌中HER2过表达细胞的设计和评估
6. Combining AZD8931 a novel EGFR/HER2/HER3 signalling inhibitor with AZD5363 limits AKT inhibitor induced feedback and enhances antitumour efficacy in HER2-amplified breast cancer models [O] . CLAIRE CRAFTER, JOHN P. VINCENT, ERIC TANG, -1

机译：将新型EGFR / HER2 / HER3信号抑制剂AZD8931与AZD5363结合使用可限制AKT抑制剂诱导的反馈并增强在HER2扩增的乳腺癌模型中的抗肿瘤功效
7. Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases [O] . D. P. Kodack, E. Chung, H. Yamashita, 2012

机译：HER2和VEGFR2的组合靶向治疗HER2-扩增乳腺癌脑转移的有效治疗方法

Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors

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