首页> 外文OA文献 >BM6, a new semi-synthetic vinca alkaloid, exhibits its potent in vivo anti-tumor activities via its high binding affinity for tubulin and improved pharmacokinetic profiles

【2h】

BM6, a new semi-synthetic vinca alkaloid, exhibits its potent in vivo anti-tumor activities via its high binding affinity for tubulin and improved pharmacokinetic profiles

机译：新型半合成的vinca生物碱BM6通过其对微管蛋白的高结合亲和力和改善的药代动力学谱来表现出其高效的体内抗肿瘤活性

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
引文网络
相似文献
相关主题

著录项

作者
Weihong Li; Yong Shao; Lihong Hu; Xiongwen Zhang; Yi Chen; Linjiang Tong; Chuan Li; Xu Shen; Jian Ding;
展开▼
作者单位

展开▼
年度 2007
总页数
原文格式 PDF
正文语种
中图分类

相似文献

外文文献
专利

1. -NH-dansyl isocolchicine exhibits a significantly improved tubulin-binding affinity and microtubule inhibition in comparison to isocolchicine by binding tubulin through its A and B rings [J] . Das L, Datta AB, Gupta S, Biochemistry . 2005,第9期

机译：-NH-丹磺酰基异秋水仙碱与异秋水仙碱相比，通过其A环和B环结合微管蛋白，显示出显着改善的微管蛋白结合亲和力和微管抑制作用
2. 449 POSTER In vivo evaluation of ALB 109564, a novel tubulin inhibitor with improved efficacy over existing members of the Vinca alkaloid class [J] . M.Wolf, R.K.Johnson, D.Xie, European Journal of Cancer Supplements . 2008,第12期

机译：449 POSTER ALB 109564的体内评估，一种新型微管蛋白抑制剂，具有比长春花生物碱类现有成员更高的功效
3. Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: Improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy [J] . KawakitaY., MiwaK., SetoM., Bioorganic and medicinal chemistry . 2012,第20期

机译：吡咯并[3,2-d]嘧啶HER2 / EGFR双重抑制剂的设计与合成：改善体内有效抗肿瘤功效的理化和药代动力学
4. Design, Synthesis, Biophysical and Structure-Activity Properties of a Novel Dual MDM2 and MDMX Targeting Stapled α-Helical Peptide: ATSP-7041 Exhibits Potent In Vitro and In Vivo Efficacy in Xenograft Models of Human Cancer [C] . V. Guerlavais, K. Darlak, B. Graves American Peptide Symposium . 2013

机译：新型双MDM2和MDMX靶向吻合α-螺旋肽的设计，合成，生物物理和结构 - 活性特性：ATSP-7041在体外表现出效率和体内人类癌症的模型
5. The Novel Tubulin Polymerization Inhibitor MHPT Exhibits Selective Anti-Tumor Activity against Rhabdomyosarcoma In Vitro and In Vivo [O] . Yan Mu, Yin Liu, Liwen Li, -1

机译：新型微管蛋白聚合抑制剂MHPT在体外和体内表现出针对横纹肌肉瘤的选择性抗肿瘤活性。
6. Tubulin-based structure-affinity relationships for antimitotic Vinca alkaloids [O] . Coderch Claire, Morreale Antonio, Gago Federico 2015

机译：基于微管蛋白的抗有丝分裂长春花生物碱的结构亲和力关系

BM6, a new semi-synthetic vinca alkaloid, exhibits its potent in vivo anti-tumor activities via its high binding affinity for tubulin and improved pharmacokinetic profiles

著录项

引文网络

相似文献

相关主题

期刊订阅